Mark Tingey
Temple University
7 Papers
33 Citations
Mark Tingey is an academic researcher from Temple University. The author has contributed to research in topics: Inner membrane & Sting. The author has an hindex of 3, co-authored 7 publications.
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Papers
Distinct roles of nuclear basket proteins in directing the passage of mRNA through the nuclear pore
Yichen Li,Vasilisa Aksenova,Mark Tingey,Jingjie Yu,Ping Ma,Alexei Arnaoutov,Shane Chen,Mary Dasso,Weidong Yang +8 more
TL;DR: In this article, the authors quantified the native copies of nuclear basket (BSK) proteins (Nup153, Nup50, and Tpr) prior to knocking them down in a highly specific manner via an auxin-inducible degron strategy.
32
Casting a Wider Net: Differentiating between Inner Nuclear Envelope and Outer Nuclear Envelope Transmembrane Proteins.
TL;DR: This review will evaluate the current tools and methodologies available to address the distribution and abundance of nuclear envelope transmembrane proteins on the NE.
21
3D Tracking-Free Approach for Obtaining 3D Super-Resolution Information in Rotationally Symmetric Biostructures.
TL;DR: This article introduces a simple approach, without using 3D super-resolution microscopy or real-time 3D particle tracking, to estimate 3D sub-diffraction-limited structural or dynamic information in rotationally symmetric biostructures.
16
Protocol for single-molecule fluorescence recovery after photobleaching microscopy to analyze the dynamics and spatial locations of nuclear transmembrane proteins in live cells.
Mark Tingey,Yichen Li,Weidong Yang +2 more
- 30 Apr 2021
TL;DR: Mudumbi et al. as discussed by the authors described a step-by-step protocol for smFRAP on nuclear envelope transmembrane proteins on the inner nuclear membrane and outer nuclear membrane in live cells.
6
STING Nuclear Partners Contribute to Innate Immune Signalling Responses
Charles R. Dixon,Poonam Malik,J. I. de las Heras,Natalia Saiz-Ros,F. de Lima Alves,Mark Tingey,E. R. Gaunt,Christine Richardson,David A. Kelly,Martin W. Goldberg,Greg J. Towers,Weidong Yang,Juri Rappsilber,Paul Digard,Eric C. Schirmer +14 more
TL;DR: In this article, the inner nuclear membrane of STING was found to increase mobility and changes localization upon IIR activation both from dsDNA and poly(I:C) stimuli.