Mark S.P. Sansom
University of Oxford
676 Papers
8.3K Citations
Mark S.P. Sansom is an academic researcher from University of Oxford. The author has contributed to research in topics: Lipid bilayer & Chemistry. The author has an hindex of 92, co-authored 647 publications. Previous affiliations of Mark S.P. Sansom include University of Toronto & University of Nottingham.
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Papers
HOLE: a program for the analysis of the pore dimensions of ion channel structural models.
TL;DR: A method (HOLE) that allows the analysis of the dimensions of the pore running through a structural model of an ion channel is presented and can be used to predict the conductance of channels using a simple empirically corrected ohmic model.
1.7K
Computational Modeling of Realistic Cell Membranes
Siewert J. Marrink,Valentina Corradi,Paulo C. T. Souza,Helgi I. Ingólfsson,D. Peter Tieleman,Mark S.P. Sansom +5 more
TL;DR: The state of the art in the field of realistic membrane simulations is reviewed and the current limitations and challenges ahead are discussed.
612
Liquid–vapor oscillations of water in hydrophobic nanopores
TL;DR: The results suggest that simulations aimed at collective phenomena such as hydrophobic effects may require simulation times >50 ns, because for water in confined geometries, it is not possible to extrapolate from bulk or short time behavior to longer time scales.
454
Acquisition of siderophores in gram-negative bacteria
TL;DR: Bacteria have evolved sophisticated mechanisms whereby the concerted actions of receptor, transporter and energy-transducing proteins ensure that there is a sufficient supply of iron-containing compounds, such as siderophores, in the cell.
378