Mark K. Devries
University of Wisconsin-Madison
12 Papers
36 Citations
Mark K. Devries is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Viral replication & Rhinovirus. The author has an hindex of 6, co-authored 7 publications.
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Papers
Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication.
Yury A. Bochkov,Kelly Watters,Shamaila Ashraf,Theodor F. Griggs,Mark K. Devries,Daniel J. Jackson,Ann C. Palmenberg,James E. Gern +7 more
TL;DR: It is discovered that expression of human cadherin-related family member 3 (CDHR3), a transmembrane protein with yet unknown biological function, enables RV-C binding and replication in normally unsusceptible host cells, and suggests that rs6967330 mutation could be a risk factor for RV- C wheezing illnesses.
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Sirt3 Promotes the Urea Cycle and Fatty Acid Oxidation during Dietary Restriction
William C. Hallows,Wei Yu,Brian C. Smith,Mark K. Devries,James J. Ellinger,Shinichi Someya,Michael R. Shortreed,Tomas A. Prolla,John L. Markley,Lloyd M. Smith,Shimin Zhao,Kun-Liang Guan,Kun-Liang Guan,John M. Denu +13 more
TL;DR: In this article, the authors utilized acetyl-peptide arrays and metabolomic analyses to identify substrates of the mitochondrial deacetylase Sirt3, and found that under low energy input, sirt3 modulates mitochondria by promoting amino acid catabolism and β-oxidation.
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Structure and biochemical functions of SIRT6.
Patricia W. Pan,Jessica L. Feldman,Mark K. Devries,Aiping Dong,Aled M. Edwards,Aled M. Edwards,John M. Denu +6 more
TL;DR: Evidence is provided that SIRT6-dependent histone deacetylation produces O-acetyl-ADP-ribose but at a rate ∼1,000 times slower than other highly active sirtuins, which implies a unique activating mechanism and/or the possibility that Sirt6 could act as an NAD+ metabolite sensor.
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Innate Immune Responses to Rhinovirus are Reduced by the High-Affinity IgE Receptor in Allergic Asthmatic Children
S.R. Durrani,Daniel J. Montville,Allison S. Pratt,Sanjukta Sahu,Mark K. Devries,Victoria Rajamanickam,Ronald E. Gangnon,Michelle A. Gill,James E. Gern,Robert F. Lemanske,Daniel J. Jackson +10 more
TL;DR: Allergic asthmatic children have impaired innate immune responses to HRV that correlate with increased FcεRI expression on pDCs and are reduced by Fc�RI cross-linking, which likely increase susceptibility to HRv-induced wheezing and asthma exacerbations.
Enhanced Neutralizing Antibody Responses to Rhinovirus C and Age-Dependent Patterns of Infection.
Timothy Choi,Mark K. Devries,Leonard B. Bacharier,William W. Busse,Carlos A. Camargo,Robyn T. Cohen,Gregory P. DeMuri,Michael D. Evans,Anne M. Fitzpatrick,Peter J. Gergen,Kristine Grindle,Rebecca S. Gruchalla,Tina V. Hartert,Kohei Hasegawa,Gurjit K. Khurana Hershey,Patrick G. Holt,Kiara Homil,Tuomas Jartti,Tuomas Jartti,Meyer Kattan,Carolyn M. Kercsmar,Haejin Kim,Ingrid A. Laing,Petra LeBeau,Kristine E. Lee,Peter N. Le Souëf,Andrew H. Liu,David T. Mauger,Carole Ober,Tressa Pappas,Shilpa J. Patel,Wanda Phipatanakul,Jacqueline A. Pongracic,Christine M. Seroogy,Peter D. Sly,Christopher J. Tisler,Ellen R. Wald,Robert J. Wood,Ronald E. Gangnon,Daniel J. Jackson,Robert F. Lemanske,James E. Gern,Yury A. Bochkov +42 more
TL;DR: In this paper, the authors identify how age and other individual-level factors affect the performance of rhinovirus infection and respiratory illnesses ranging from the common cold to severe wheezing.
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