Mark J. Bartlett
Stanford University
18 Papers
121 Citations
Mark J. Bartlett is an academic researcher from Stanford University. The author has contributed to research in topics: Catalysis & Enantioselective synthesis. The author has an hindex of 9, co-authored 18 publications. Previous affiliations of Mark J. Bartlett include Hoffmann-La Roche & Victoria University, Australia.
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Papers
ProPhenol-Catalyzed Asymmetric Additions by Spontaneously Assembled Dinuclear Main Group Metal Complexes
Barry M. Trost,Mark J. Bartlett +1 more
TL;DR: The development and application of the ProPhenol ligand for asymmetric additions of both carbon- and heteroatom-based nucleophiles to various electrophiles to help facilitate catalytic enantioselective addition reactions, including aldol and alkynylation reactions.
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Cooperative Tandem Catalysis by an Organometallic Complex and a Metalloenzyme
TL;DR: Combination of a metathesis catalyst and a P450 enzyme lead to a dynamic equilibration of alkenes and a selective epoxidation of the cross-metathesis products, which show the potential of combining the two classes of catalysts for synthetic transformations.
137
Thionium Ion Initiated Medium-Sized Ring Formation: The Total Synthesis of Asteriscunolide D
TL;DR: A stereospecific thioether activation-elimination protocol was developed for selective E-olefin formation, thus providing access to the most biologically active asteriscunolide.
Development of a One-Pot Tandem Reaction Combining Ruthenium-Catalyzed Alkene Metathesis and Enantioselective Enzymatic Oxidation To Produce Aryl Epoxides
TL;DR: A tandem chemoenzymatic transformation that combines alkene metathesis with enzymatic epoxidation to provide aryl epoxides is reported, which converts a mixture of alkenes into a single epoxide product in high enantioselectivity and moderate yields.
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Development of Zn–ProPhenol‐Catalyzed Asymmetric Alkyne Addition: Synthesis of Chiral Propargylic Alcohols
TL;DR: The development of a general and practical zinc-catalyzed enantioselective alkyne addition methodology is reported, with new insights into the mechanism of this reaction resulting in a significant reduction in reagent stoichiometry, enabling the use of precious alkynes and avoiding theUse of excess dimethylzinc.
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