Mark E. Anderson
Johns Hopkins University
5 Papers
79 Citations
Mark E. Anderson is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Ca2+/calmodulin-dependent protein kinase & Health care. The author has an hindex of 4, co-authored 5 publications. Previous affiliations of Mark E. Anderson include Duke University & Vanderbilt University.
Chat about Author
Papers
Progress toward the prevention and treatment of atrial fibrillation: A summary of the Heart Rhythm Society Research Forum on the Treatment and Prevention of Atrial Fibrillation, Washington, DC, December 9-10, 2013.
David R. Van Wagoner,Jonathan P. Piccini,Christine M. Albert,Mark E. Anderson,Emelia J. Benjamin,Bianca J. J. M. Brundel,Robert M. Califf,Hugh Calkins,Peng Sheng Chen,Nipavan Chiamvimonvat,Dawood Darbar,Lee L. Eckhardt,Patrick T. Ellinor,Derek V. Exner,Richard I. Fogel,Anne M. Gillis,Jeff S. Healey,Stefan H. Hohnloser,Hooman Kamel,David A. Lathrop,Gregory Y.H. Lip,Gregory Y.H. Lip,Reena Mehra,Sanjiv M. Narayan,Jeffrey E. Olgin,Douglas L. Packer,Nicholas S. Peters,Dan M. Roden,Heather M. Ross,Robert S. Sheldon,Xander H.T. Wehrens +30 more
TL;DR: Although largely focused on primary prevention of AF, the paper also addresses some aspects of secondary prevention of recurrent AF due to the continuum of risk factors that contribute to arrhythmogenesis, permissive left atrial (LA) substrates, and the emergence of AF.
89
Progress toward the prevention and treatment of atrial fibrillation: A summary of the Heart Rhythm Society Research Forum on the Treatment and Prevention of Atrial Fibrillation, Washington, DC, December 9-10, 2013.
David R. Van Wagoner,Jonathan P. Piccini,Christine M. Albert,Mark E. Anderson,Emelia J. Benjamin,Bianca J. J. M. Brundel,Robert M. Califf,Hugh Calkins,Peng Sheng Chen,Nipavan Chiamvimonvat,Dawood Darbar,Lee L. Eckhardt,Patrick T. Ellinor,Derek V. Exner,Richard I. Fogel,Anne M. Gillis,Jeff S. Healey,Stefan H. Hohnloser,Hooman Kamel,David A. Lathrop,Gregory Y.H. Lip,Gregory Y.H. Lip,Reena Mehra,Sanjiv M. Narayan,Jeffrey E. Olgin,Douglas L. Packer,Nicholas S. Peters,Dan M. Roden,Heather M. Ross,Robert S. Sheldon,Xander H.T. Wehrens +30 more
- 01 Jan 2015
TL;DR: The Heart Rhythm Society convened a research symposium on December 9-10, 2013, in Washington, DC, that focused on the prevention of atrial fibrillation (AF) as well as AF-related stroke and morbidity as discussed by the authors.
79
Oxidized CaMKII (Ca2+/Calmodulin-Dependent Protein Kinase II) Is Essential for Ventricular Arrhythmia in a Mouse Model of Duchenne Muscular Dystrophy.
Qiongling Wang,Ann P. Quick,Shuyi Cao,Julia O. Reynolds,David Y. Chiang,David L. Beavers,Na Li,Guoliang Wang,George G. Rodney,Mark E. Anderson,Xander H.T. Wehrens +10 more
TL;DR: Inhibition of reactive oxygen species or ox-CaMKII protects against proarrhythmic intracellular Ca2+ handling and prevents ventricular arrhythmia in a mouse model of Duchenne muscular dystrophy.
44
receptors(RyR2s)ishypothesizedtocontributetoarrhythmogenesisinAF,butthemolecularmechanisms areincompletelyunderstood.Here,wehaveshownthatmicewithageneticgain-of-functiondefectinRyr2 (whichwetermedRyr2 R176Q/+ mice)didnotexhibitspontaneousAFbutthatrapidatrialpacingunmasked anincreasedvulnerabilitytoAFinthesemicecomparedwithwild-typemice.Rapidatrialpacingresulted inincreasedCa 2+ /calmodulin-dependentproteinkinaseII(CaMKII)phosphorylationofRyR2,whileboth pharmacologicandgeneticinhibitionofCaMKIIpreventedAFinducibilityinRyr2 R176Q/+ mice.Thisresult
Mihail G. Chelu,Satyam Sarma,Sufen Wang,Ralph J. van Oort,Darlene G. Skapura,Na Li,Marco Santonastasi,Frank Ulrich Müller,Wilhelm Schmitz,Ulrich Schotten,Mark E. Anderson,Dobromir Dobrev,Xander H.T. Wehrens +12 more
- 01 Jan 2009