Mark Blaxter
University of Edinburgh
6 Papers
42 Citations
Mark Blaxter is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Genome & Small nuclear RNA. The author has an hindex of 4, co-authored 6 publications.
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Papers
The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets
Christelle Godel,Sujai Kumar,Georgios Koutsovoulos,Philipp Ludin,Daniel Nilsson,Francesco Comandatore,Nicola Wrobel,Marian Thompson,Christoph D. Schmid,Susumu Goto,Frédéric Bringaud,Adrian J. Wolstenholme,Claudio Bandi,Christian Epe,Ronald Kaminsky,Mark Blaxter,Pascal Mäser +16 more
TL;DR: The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets, and the differential presence of anabolic pathways such as heme and nucleotide biosynthesis hints at the intricate metabolic interrelationship between the heartworms and Wolbachia.
The transcriptomic basis of oviposition behaviour in the parasitoid wasp Nasonia vitripennis
TL;DR: In this paper, the authors compared the whole-body transcriptomes of resting or ovipositing female Nasonia using a DeepSAGE gene expression approach on the Illumina sequencing platform.
Additional file 15: Figure S7. of The genome of the yellow potato cyst nematode, Globodera rostochiensis, reveals insights into the basis of parasitism and virulence
Sebastian Eves-van den Akker,Dominik R. Laetsch,Peter Thorpe,Catherine J. Lilley,Etienne Danchin,Martine Da Rocha,Corinne Rancurel,Nancy Holroyd,James Cotton,Amir Szitenberg,Eric Grenier,Josselin Montarry,Benjamin Mimee,Marc-Olivier Duceppe,Ian Boyes,Jessica Marvin,Laura M. Jones,Hazijah Yusup,JoĂŤl Lafond-Lapalme,Magali Esquibet,Michael Sabeh,Michael Rott,Hein Overmars,A.M. Finkers-Tomczak,Geert Smant,Georgios Koutsovoulos,Vivian Blok,Sophie Mantelin,Peter J. A. Cock,Wendy S. Phillips,Bernard Henrissat,Peter E. Urwin,Mark Blaxter,John Jones +33 more
- 01 Jan 2016
TL;DR: In this paper, a high quality genome assembly for Globodera rostochiensis was generated, identifying putative effectors and horizontal gene transfer events, map gene expression through the life cycle focusing on key parasitic transitions and sequence the genomes of eight populations including four additional pathotypes to identify variation.
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2012 Landes Bioscience. Do not distribute. Toward 959 nematode genomes
Sujai Kumar,Georgios Koutsovoulos,Gaganjot Kaur,Mark Blaxter +3 more
- 01 Jan 2012
TL;DR: It is hoped that a nematode phylogeny with (at least) 959 sequenced species will underpin further advances in understanding the origins of parasitism, the dynamics of genomic change and the adaptations that have made Nematoda one of the most successful animal phyla.
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Evolutionary analysis implicates RNA polymerase II pausing and chromatin structure in nematode piRNA biogenesis
Toni Beltran,C. Barruso,T. Y. Birkle,Leslie Stevens,Hillel T. Schwartz,Paul W. Sternberg,Hélène Fradin,Kristin C. Gunsalus,Fabio Piano,J. Cotton,Enrique Martinez-Perez,Mark Blaxter,Peter Sarkies +12 more
TL;DR: It is shown that the piRNA upstream motif is derived from core promoter elements controlling snRNA biogenesis, which synergise with the chromatin environment to control piRNA precursor transcription.