Mark B. Harvey
Queensland University of Technology
7 Papers
47 Citations
Mark B. Harvey is an academic researcher from Queensland University of Technology. The author has contributed to research in topics: Blastocyst & Receptor. The author has an hindex of 7, co-authored 7 publications.
Chat about Author
Papers
Elevated concentration of TNF-α induces trophoblast differentiation in mouse blastocyst outgrowths
Eliza Whiteside,Kerry J. Boucaut,Alison Teh,Juanita Garcia-Aragon,Mark B. Harvey,Adrian C. Herington +5 more
TL;DR: It is reported that elevated TNF-α restricts ICM proliferation in the blastocyst and changes the ratio of mononucleated to multinucleated trophoblast cells.
24
Temporal and Tissue-Specific Expression of Kallikrein (Klk) Genes and Identification of a Novel Klk Messenger Ribonucleic Acid Transcript during Early Development in the Mouse
TL;DR: The distinct gene- and tissue-specific expression patterns presented in this study, in conjunction with the well-characterized roles of kallikreins in regulation of protein activation, ECM degradation, and proliferative events, suggests the involvement of the k allikrein gene family during early development.
Urokinase-type plasminogen activator (uPA) and matrix metalloproteinase-9 (MMP-9) expression and activity during early embryo development in the cow.
Eliza Whiteside,Michael Kan,Michael M. Jackson,Jeremy G. Thompson,Catherine Mcnaughton,Adrian C. Herington,Mark B. Harvey +6 more
TL;DR: The results of this study suggest that these ECM proteinases have a role prior to implantation in the cow, in contrast to that exhibited by mouse, sheep and pig embryos.
16
Matrix metalloproteinase-9 maps to the distal end of chromosome 2 in the mouse.
Kevin J. Leco,Mark B. Harvey,Aileen Hogan,Neal G. Copeland,Debra J. Gilbert,Nancy A. Jenkins,Dylan R. Edwards,Gilbert A. Schultz +7 more
TL;DR: Loss of MMP-9 activity in parthenogenetic blastocysts does not appear to be due to imprinting but, rather, due to a defect of trophoblast giant cell proliferation and differentiation.
9
Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-3 Are Key Regulators of Extracellular Matrix Degradation by Mouse Embryos
TL;DR: Functional evidence is provided that in vitro ECM degradation is regulated by embryo-derived MMP-9 and ECM-derived TIMP-3.