Mark Ambrose
University of Tasmania
16 Papers
88 Citations
Mark Ambrose is an academic researcher from University of Tasmania. The author has contributed to research in topics: DNA repair & DNA damage. The author has an hindex of 9, co-authored 16 publications. Previous affiliations of Mark Ambrose include University of California, Los Angeles & La Trobe University.
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Papers
Broad spectrum antimicrobial activity of functionalized polyanilines.
TL;DR: The results appear to indicate that the antimicrobial effects of fPANI, in part at least, might stem from their ability to target the operations of multiple and diverse cellular processes, and suggest that fPani could be useful ingredients for biomaterials used in the development of food packaging and medical devices.
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The adaptive imbalance in base excision–repair enzymes generates microsatellite instability in chronic inflammation
Lorne J. Hofseth,Mohammed A. Khan,Mark Ambrose,Olga Nikolayeva,Meng Xu-Welliver,Maria Kartalou,S. Perwez Hussain,Richard B. Roth,Xiaoling Zhou,Leah E. Mechanic,Irit Zurer,Varda Rotter,Leona D. Samson,Curtis C. Harris +13 more
TL;DR: In this article, the authors examined tissues from noncancerous colons of ulcerative colitis patients to determine the activity of two base excision-repair enzymes, AAG, the major 3-methyladenine DNA glycosylase, and APE1, the apurinic site endonuclease, and the prevalence of microsatellite instability.
Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions
Mark Ambrose,Richard A. Gatti +1 more
TL;DR: Appreciating ATM roles helps to provide new insights into the diverse clinical phenotypes exhibited by A-T patients-children and adults alike-which include neurodegeneration, high cancer risk, adverse reactions to radiation and chemotherapy, pulmonary failure, immunodeficiency, glucose transporter aberrations, insulin-resistant diabetogenic responses, and distinct chromosomal and chromatin changes.
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Learning global health: a pilot study of an online collaborative intercultural peer group activity involving medical students in Australia and Indonesia
TL;DR: This pilot study demonstrated that while intercultural collaborative peer learning activities like RIPPLE are feasible, they require robust logistical support and an awareness of the need to manage curriculum alignment in ways that facilitate more effective student engagement.
Functionalized polyanilines disrupt Pseudomonas aeruginosa and Staphylococcus aureus biofilms.
Marija Gizdavic-Nikolaidis,Joanne Pagnon,Naseem Ali,Reuben Sum,Noel W. Davies,LF Roddam,Mark Ambrose +6 more
TL;DR: The results of the present study suggest that the broad antimicrobial activities of fPANI could be developed further and used in some novel ways to construct medical devices and/or industrial equipment that are refractory to colonization by biofilm-forming bacteria.
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