Mark A. Fraser
Australian National University
6 Papers
2 Citations
Mark A. Fraser is an academic researcher from Australian National University. The author has contributed to research in topics: Middle age & Population. The author has an hindex of 3, co-authored 6 publications.
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Papers
A systematic review and meta-analysis of longitudinal hippocampal atrophy in healthy human ageing.
TL;DR: Hippocampal atrophy rates increase with age with the largest increases occurring from midlife onwards, and manual segmentation approaches result in higher measured atrophy levels.
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Objectively measured physical activity is associated with dorsolateral prefrontal cortex volume in older adults.
Joseph M. Northey,Joseph M. Northey,Ben Rattray,Ben Rattray,Kate L. Pumpa,Disa Pryor,Mark A. Fraser,Marnie Shaw,Kaarin J. Anstey,Kaarin J. Anstey,Kaarin J. Anstey,Nicolas Cherbuin +11 more
TL;DR: It is suggested that an intensity-dependent relationship may exist, whereby a greater duration of MVPA, perhaps driven by moderate-intensity PA, is associated with preserved gray matter volume in frontal regions of the brain.
27
Longitudinal Effects of Physical Activity Change on Hippocampal Volumes over up to 12 Years in Middle and Older Age Community-Dwelling Individuals
Mark A. Fraser,Erin Walsh,Marnie Shaw,Kaarin J. Anstey,Kaarin J. Anstey,Kaarin J. Anstey,Nicolas Cherbuin +6 more
TL;DR: In this paper, the authors investigated the long-term associations between changes in physical activity levels and hippocampal volumes over time, while considering the influence of age, sex, and APOE-e4 genotype.
6
Assumption-Free Assessment of Corpus Callosum Shape: Benchmarking and Application
TL;DR: Elliptical Fourier analysis, particularly in combination with principal component analysis, is a powerful, assumption-free and intuitive method of quantifying global shape of the corpus callosum and shows great promise for shape analysis in neuroimaging more broadly.
Longitudinal trajectories of hippocampal volume in middle to older age community dwelling individuals.
Mark A. Fraser,Erin Walsh,Marnie Shaw,Walter P. Abhayaratna,Kaarin J. Anstey,Perminder S. Sachdev,Nicolas Cherbuin +6 more
TL;DR: Investigation of hippocampal change in a generally healthy community-living population of middle and older age individuals found men tended to experience steeper declines than women in middle age only and women in older age only, and three subgroups of individuals following different trajectories were identified.