Mariska E. A. van Dijk
Utrecht University
9 Papers
143 Citations
Mariska E. A. van Dijk is an academic researcher from Utrecht University. The author has contributed to research in topics: Immune system & T cell. The author has an hindex of 7, co-authored 9 publications. Previous affiliations of Mariska E. A. van Dijk include Boston Children's Hospital.
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Papers
A Multiplex Immunoassay for Human Adipokine Profiling
Henk S. Schipper,Wilco de Jager,Mariska E. A. van Dijk,Jenny Meerding,Pierre M. J. Zelissen,Roger A.H. Adan,Berent J. Prakken,Eric Kalkhoven +7 more
TL;DR: The findings underscore the relevance of the novel adipokines cathepsin S and chemerin, but foremost the potential of this novel method for both comprehensive adipokine profiling in large patient cohorts and for biological discovery.
Characterization of the CD8+ T cell responses directed against respiratory syncytial virus during primary and secondary infection in C57BL/6 mice
Michaël V. Lukens,Erwin A.W. Claassen,Patricia M. A. de Graaff,Mariska E. A. van Dijk,Peter Hoogerhout,Mireille Toebes,Ton N. Schumacher,Robbert van der Most,Jan L. L. Kimpen,Grada M. van Bleek +9 more
TL;DR: The specificity, level and functional capabilities of CD8+ T cells during primary and secondary responses in lung parenchyma, airways and spleens of C57BL/6 mice were characterized and epitopes were recognized originating from the matrix, fusion, nucleo- and attachment proteins.
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HLA-DP4 presents an immunodominant peptide from the RSV G protein to CD4 T cells
Patricia M. A. de Graaff,Jojanneke Heidema,Martien C. M. Poelen,Mariska E. A. van Dijk,Michaël V. Lukens,Sjef P.J van Gestel,Judith Reinders,Erik H. Rozemuller,Marcel G.J. Tilanus,Peter Hoogerhout,Cécile A. C. M. van Els,Robbert van der Most,Jan L. L. Kimpen,Grada M. van Bleek +13 more
TL;DR: An immunodominant epitope in the conserved region of the G protein encompassing amino acid residues 162-175 is identified and in some patients, a mixed Th1/Th2 response against this epitope was found in bronchoalveolar lavage samples during primary RSV infections.
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Matrix metalloproteinases as targets for the immune system during experimental arthritis.
Jolanda H. M. van Bilsen,Josée P A Wagenaar-Hilbers,Mayken C. J. T. Grosfeld-Stulemeijer,Maarten J. F. van der Cammen,Mariska E. A. van Dijk,Willem van Eden,Marca H. M. Wauben +6 more
TL;DR: MMPs play a pivotal role as target for T and B cells during the development of inflammatory arthritis, and the presence of Abs to MMP-3 during the course of adjuvant arthritis is demonstrated.
Successful immunotherapy with matrix metalloproteinase-derived peptides in adjuvant arthritis depends on the timing of peptide administration.
Jolanda H. M. van Bilsen,Josée P A Wagenaar-Hilbers,Maarten J. F. van der Cammen,Mariska E. A. van Dijk,Willem van Eden,Marca H. M. Wauben +5 more
TL;DR: The present study shows the possible usefulness of MMP peptides for immunotherapy, however, a clear understanding of proper timing of peptide administration is crucial for the development of such therapies.