Marion Vanneste
Roy J. and Lucille A. Carver College of Medicine
18 Papers
38 Citations
Marion Vanneste is an academic researcher from Roy J. and Lucille A. Carver College of Medicine. The author has contributed to research in topics: Metastasis & Medicine. The author has an hindex of 6, co-authored 11 publications. Previous affiliations of Marion Vanneste include University of Iowa.
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Papers
Cancer Cells Resist Mechanical Destruction in Circulation via RhoA/Actomyosin-Dependent Mechano-Adaptation.
Devon L. Moose,Devon L. Moose,Benjamin L Krog,Benjamin L Krog,Tae-Young Kim,Lei Zhao,Sophia Williams-Perez,Gretchen Burke,Lillian Rhodes,Marion Vanneste,Patrick Breheny,Mohammed M. Milhem,Christopher S. Stipp,Christopher S. Stipp,Amy C. Rowat,Michael D. Henry +15 more
TL;DR: It is demonstrated that cancer cells activate RhoA in response to FSS, which protects them from FSS-induced plasma membrane damage, and that viable CTCs actively resist destruction by hemodynamic forces and are likely to be more mechanically robust than is commonly thought.
66
High content screening identifies monensin as an EMT-selective cytotoxic compound.
Marion Vanneste,Qin Huang,Mengshi Li,Devon L. Moose,Lei Zhao,Mark Stamnes,Mark Stamnes,Michael K. Schultz,Michael K. Schultz,Meng Wu,Michael D. Henry +10 more
TL;DR: Increased monensin sensitivity in EMT-like cells is associated with elevated uptake of 3H-monensin compared to resistant cells, and Gene Set Enrichment Analysis identified EMT as the top enriched gene set in the sensitive group.
Prolactin-induced protein is required for cell cycle progression in breast cancer.
Ali Naderi,Marion Vanneste +1 more
TL;DR: It is demonstrated that PIP is required for the progression through G1 phase, mitosis, and cytokinesis in luminal A, luminal B, and molecular apocrine breast cancer cells and provides a rationale for exploring PIP inhibition as a therapeutic approach in breast cancer that can potentially target microtubule polymerization.
31
Prolactin-Induced Protein regulates cell adhesion in breast cancer.
Marion Vanneste,Ali Naderi +1 more
TL;DR: It is found that PIP expression is necessary for the formation of α-actinin/actin-rich podosomes at the adhesion-sites of breast cancer cells.
9
Locally invasive, castrate-resistant prostate cancer in a Pten/Trp53 double knockout mouse model of prostate cancer monitored with non-invasive bioluminescent imaging.
Courtney Yong,Devon L. Moose,Nadine Bannick,Wade R. Gutierrez,Marion Vanneste,Robert U. Svensson,Patrick Breheny,James A. Brown,Rebecca D. Dodd,Rebecca D. Dodd,Michael B. Cohen,Michael D. Henry +11 more
TL;DR: It is shown that, consistent with previous reports, deletion of both Pten and Trp53 on a C57BL/6 background accelerates tumor growth and results in both the loss of androgen receptor expression and castrate resistant tumors as compared with loss of Pten alone.