Mariola Zagor
Medical University of Warsaw
9 Papers
4 Citations
Mariola Zagor is an academic researcher from Medical University of Warsaw. The author has contributed to research in topics: Medicine & RAGE (receptor). The author has an hindex of 5, co-authored 8 publications.
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Papers
PRAME expression in head and neck cancer correlates with markers of poor prognosis and might help in selecting candidates for retinoid chemoprevention in pre-malignant lesions.
Miroslaw J. Szczepanski,Albert B. DeLeo,Michał Łuczak,Marta Molinska-Glura,Jan Misiak,Bronislawa Szarzynska,Grzegorz Dworacki,Mariola Zagor,Natalia Rozwadowska,Maciej Kurpisz,Antoni Krzeski,Aleksandra Kruk-Zagajewska,Tomasz Kopeć,Jacek Banaszewski,Theresa L. Whiteside +14 more
TL;DR: Elevated PRAME expression associates with clinicopathologic markers of poor outcome in HNSCC and might identify potential candidates with pre-cancerous lesions for chemoprevention with retinoids.
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The correlation of TAS2R38 gene variants with higher risk for chronic rhinosinusitis in Polish patients.
TL;DR: The hypothesis that airway bitter T2Rs are an innovative sphere of human respiratory innate protection is provided, as TAS2R38 polymorphism may influence the susceptibility to CRS.
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Expression of the Receptor for Advanced Glycation End Products, a Target for High Mobility Group Box 1 Protein, and its Role in Chronic Recalcitrant Rhinosinusitis with Nasal Polyps
TL;DR: A receptor for advanced glycation end products (RAGE) and its ligand high mobility group box 1 (HMGB1) protein has been linked to several chronic diseases, and acts as a trigger for inflammation signaling, which is associated with increased disease severity, as well as allergy and AERD in patients with recalcitrant CRSwNP.
Molecular signaling of the HMGB1/RAGE axis contributes to cholesteatoma pathogenesis.
Miroslaw J. Szczepanski,Michal W. Luczak,Ewa Olszewska,Marta Molińska-Glura,Mariola Zagor,Antoni Krzeski,Henryk Skarżyński,Jan Misiak,Karolina Dżaman,Mikolaj Bilusiak,Tomasz Kopeć,Małgorzata Leszczyńska,Henryk Witmanowski,Theresa L. Whiteside +13 more
TL;DR: The data suggest that in cholesteatoma, HMGB1 released from stressed or necrotic epithelial cells and binding to RAGE overexpressed in keratinocytes initiates molecular signaling that culminates in pro-inflammatory cytokine release and chronic inflammation.
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High motility group box 1 (HMGB1) protein and its receptor for advanced glycation end products (RAGE) expression in chronic rhinosinusitis without nasal polyps
TL;DR: Interaction of HMGB1 and RAGE might be relevant to CRS pathomechanisms leading to sinus mucosa hyperproliferation, and might be especially related to the RAGE overexpression correlated with disease severity and allergy.