Mariko Iijima
University of Tokyo
9 Papers
13 Citations
Mariko Iijima is an academic researcher from University of Tokyo. The author has contributed to research in topics: Chemistry & Epiregulin. The author has an hindex of 3, co-authored 6 publications.
Chat about Author
Papers
Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES
Yuji Kado,Eiichi Mizohata,Satoru Nagatoishi,Mariko Iijima,Keiko Shinoda,Takamitsu Miyafusa,Taisuke Nakayama,Takuma Yoshizumi,Akira Sugiyama,Takeshi Kawamura,Young-Hun Lee,Hiroyoshi Matsumura,Hirofumi Doi,Hideaki Fujitani,Tatsuhiko Kodama,Yoshikazu Shibasaki,Kouhei Tsumoto,Tsuyoshi Inoue +17 more
TL;DR: The superimposed structure of 9E5(Fab)·EPR on the known complex structure of EGF·EGFR showed that the 9E 5( Fab) paratope overlaps with Domains I and III on the EGFR, which reveals that the EPR complex could not bind to the EGfr.
16
Construction and characterization of functional anti-epiregulin humanized monoclonal antibodies.
Young-Hun Lee,Mariko Iijima,Yuji Kado,Eiichi Mizohata,Tsuyoshi Inoue,Akira Sugiyama,Hirofumi Doi,Yoshikazu Shibasaki,Tatsuhiko Kodama +8 more
TL;DR: The data support that HM1 exerts potent antibody-dependent cellular cytotoxicity (ADCC) and may have potential for further development as a candidate therapeutic agent and research tool.
15
Epiregulin-blocking antibody inhibits epiregulin-dependent EGFR signaling.
TL;DR: The anti-EREG antibody has little effect on cell growth, but it inhibits cell adhesion of EREG-expressing autocrine cancer cell lines, suggesting that anti- EREG antibodies represent valuable tools for elucidating E REG-specific signaling pathways, and may serve as therapeutic candidates for the treatment of cancers.
13
Visualisation of Phosphate in Subcalicoblastic Extracellular Calcifying Medium and on a Skeleton of Coral by Using a Novel Probe, Fluorescein-4-Isothiocyanate-Labelled Alendronic Acid
Mariko Iijima,Jun Yasumoto,Kanami Mori-Yasumoto,Mina Yasumoto-Hirose,Akira Iguchi,Atsushi Suzuki,Nanami Mizusawa,Mitsuru Jimbo,Shugo Watabe,Ko Yasumoto +9 more
TL;DR: It is concluded that FITC-AA in ambient seawater was transferred via a paracellular pathway to SCM and then absorbed on the coral CaCO3 skeletons because FITc-AA with a high polarity group cannot permeate through cell membranes.
2
Mg-rich calcite-producing marine bacterium Pseudovibrio sp. isolated from an ascidian in coral reefs at Okinawa, Japan
Mina Yasumoto-Hirose,Ko Yasumoto,Mariko Iijima,Tomohiko Nishino,Eiko Ikemoto,Miyuki Nishijima,Chiya Numako,Tohey Matsuyama,Yoshikazu Shizuri,Kazuhiro Kogure,Shugo Watabe +10 more
TL;DR: Pseudovibrio sp.
2