Marianne Hamilton Therkildsen
University of Copenhagen
64 Papers
679 Citations
Marianne Hamilton Therkildsen is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Medicine & Immunohistochemistry. The author has an hindex of 31, co-authored 64 publications. Previous affiliations of Marianne Hamilton Therkildsen include Kantonsspital St. Gallen & Copenhagen University Hospital.
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Papers
Immunoreactive transforming growth factor alpha and epidermal growth factor in oral squamous cell carcinomas
TL;DR: In moderately to well differentiated carcinomas, the immunoreactivity was mainly confined to the cytologically more differentiated cells, thus paralleling the situation observed in the normal differentiated oral mucosa, and confirms the existence of TGF‐α, EGF, and EGF‐receptors in the majority of oral squamous cell carcinomas and their metastases.
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Can alterations in integrin and laminin-5 expression be used as markers of malignancy?
Alis Karabulut Thorup,Jesper Reibel,Morten Schiødt,Tom C. Stenersen,Marianne Hamilton Therkildsen,William G. Carter,Erik Dabelsteen +6 more
TL;DR: Biopsies from the leukoplakias and the non‐premalignant inflammatory tissue showed alterations of the expression of α3β1 and α6β4 in the basal cell layers and of laminin‐5, but there was no unequivocal expression of the adhesion molecules distinguishing between inflammatory tissue, premalignant, and malignant lesions.
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Nodal yield in selective neck dissection.
Rikke Norling,Marianne Hamilton Therkildsen,Patrick J. Bradley,Michael Bachmann Nielsen,Christian von Buchwald +4 more
TL;DR: A minimum yield of six lymph nodes for a selective neck dissection (SND) as recommended in guidelines lies in the lower range of the reported clinical nodal yields, which are currently recommended in international clinical guidelines.
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Immunohistochemical biomarkers and FDG uptake on PET/CT in head and neck squamous cell carcinoma.
Gregers Brünnich Rasmussen,Ivan R. Vogelius,Jacob H. Rasmussen,Lisa M. Schumaker,Olga B. Ioffe,Kevin J. Cullen,Barbara M. Fischer,Marianne Hamilton Therkildsen,Lena Specht,Søren M. Bentzen +9 more
TL;DR: Statistically significant correlations were observed between the expression of IHC biomarkers and maximum FDG uptake in the primary tumor.
A reverse Warburg metabolism in oral squamous cell carcinoma is not dependent upon myofibroblasts
TL;DR: In patients with OSCC, an increased expression of M CT-1 and MCT-4 in both the epithelial and stromal compartment, with almost no overlap in their spatial expression, and a large spatial overlap between α-SMA and Mct-1 in the stroma compartment, but no relationship between MCTs and myofibroblasts.
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