Mari Ohnuki
Ludwig Maximilian University of Munich
5 Papers
Mari Ohnuki is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Induced pluripotent stem cell & Reprogramming. The author has an hindex of 3, co-authored 5 publications.
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Papers
A non-invasive method to generate induced pluripotent stem cells from primate urine
Johanna Geuder,Lucas E. Wange,Aleksandar Janjic,Jessica Radmer,Philipp Janssen,Johannes W. Bagnoli,Stefan C. Müller,Artur Kaul,Mari Ohnuki,Wolfgang Enard +9 more
TL;DR: In this article, the authors reported the generation of primate induced pluripotent stem cells (iPSCs) from urine samples and showed that suspension-sendai virus transduction of reprogramming factors into urinary cells efficiently generates integration-free iPSCs which maintain their pluripotency under feeder-free culture conditions.
Present and future challenges of induced pluripotent stem cells
Mari Ohnuki,Kazutoshi Takahashi +1 more
TL;DR: In this review, the applications and future perspectives of human iPSCs are introduced and how iPSC technology has evolved along the way is shown.
TRNP1 sequence, function and regulation co-evolve with cortical folding in mammals
Zane Kliesmete,Lucas E. Wange,Beate Vieth,Esgleas M,Jessica Radmer,Hülsmann M,Hülsmann M,Johanna Geuder,Daniel Richter,Mari Ohnuki,Magdalena Götz,Ines Hellmann,Wolfgang Enard +12 more
TL;DR: In this article, the authors used cross-species association studies for the gene TRNP1 that is important for mammalian brain development and found that the rate of gene evolution is highly correlated with cortical folding across mammals and that proteins from species with more cortical folding induce higher proliferation rates in neural stem cells.
A non-invasive method to generate induced pluripotent stem cells from primate urine
Johanna Geuder,Mari Ohnuki,Lucas E. Wange,Aleksandar Janjic,Johannes W. Bagnoli,Stefan C. Müller,Artur Kaul,Wolfgang Enard +7 more
TL;DR: This study introduces a novel and efficient approach to generate iPSCs non-invasively from primate urine, which will allow to extend the zoo of species available for a comparative approach to molecular and cellular phenotypes.
The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency.
Kazutoshi Takahashi,Michiko Nakamura,Chikako Okubo,Zane Kliesmete,Mari Ohnuki,Megumi Narita,Akira Watanabe,Mai Ueda,Yasuhiro Takashima,Ines Hellmann,Shinya Yamanaka,Shinya Yamanaka +11 more
TL;DR: In this article, the authors focused on ESRG, which is known as a PSC-related HERV-H-driven long-non-coding RNAs (lncRNAs) fused with downstream neighbor genes.