Margot Zöller
Heidelberg University
252 Papers
2.9K Citations
Margot Zöller is an academic researcher from Heidelberg University. The author has contributed to research in topics: CD44 & Antigen. The author has an hindex of 56, co-authored 250 publications. Previous affiliations of Margot Zöller include Merck & Co. & German Cancer Research Center.
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Papers
Upregulation of C4.4 A Expression During Progression of Melanoma
Simone Seiter,Gunter Rappl,Uwe Reinhold,Wolfgang Tilgen,Marike J. J. G. Stassar,Margot Zöller,Margot Zöller +6 more
TL;DR: Regulated expression with highest level expression on metastases is a feature that hC4.4 A shares with the urokinase-type plasminogen activator receptor, which points towards functional activity of hC3.5 A in tumor progression.
Reduced expression of interleukin-2 decreases the frequency of alopecia areata onset in C3H/HeJ mice
Pia Freyschmidt-Paul,Kevin J. McElwee,Rolf Hoffmann,John P. Sundberg,Sabine Kissling,Susanne Hummel,Mario Vitacolonna,Annette Kopp-Schneider,Margot Zöller,Margot Zöller +9 more
TL;DR: The data suggest that AA resistance of IL-2+/- mice is because of the failure of activated leukocyte recruitment, thus pointing toward an involvement of interleukin (IL)-2 in AA pathogenesis.
Participation in normal immune responses of a metastasis-inducing splice variant of CD44
TL;DR: The observation that a protein domain that is expressed on CD44 and required for the lymphatic spread of tumor cells can catalyze an essential step in the process of lymphocyte activation supports the idea that metastasizing tumor cells mimic lymphocyte behavior.
Cloning of the human homologue of the metastasis-associated rat C4.4A
Jens Würfel,Simone Seiter,Marike J. J. G. Stassar,Andreas Claas,Rüdiger Kläs,Marc Rösel,Rachid Marhaba,Larissa Savelyeva,Manfred Schwab,Siegfried Matzku,Siegfried Matzku,Margot Zöller,Margot Zöller +12 more
TL;DR: Taking into account the high degree of homology between rat and human C.4.4A, the conformity of the expression profiles and the association of rat C4.3A with tumor progression, human C4-4A might well become a prognostic marker and possibly a target of therapy.
C4.4A as a candidate marker in the diagnosis of colorectal cancer.
Claudia Paret,Dagmar Hildebrand,Jürgen Weitz,Annette Kopp-Schneider,A Kuhn,A Beer,Richard E. Hautmann,Margot Zöller,Margot Zöller +8 more
TL;DR: By de novo expression in colonic cancer tissue, C4.4A is considered as a candidate diagnostic marker in colorectal cancer, which possibly can be detected in body fluids.