Margaret E. Hogan
8 Papers
147 Citations
Margaret E. Hogan is an academic researcher. The author has contributed to research in topics: Keratin & Laboratory mouse. The author has an hindex of 7, co-authored 8 publications.
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Papers
•Journal Article
Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development
Laura A. Hansen,Natalie Alexander,Margaret E. Hogan,John P. Sundberg,Andrzej A. Dlugosz,David W. Threadgill,Terry Magnuson,Stuart H. Yuspa +7 more
TL;DR: Ethelial expression of the EGFR is important in delaying follicular differentiation, may serve to protect the hair follicle from immunological reactions, and modifies both normal and wound-induced epidermal proliferation but seems dispensable for follicular proliferation.
235
Angora mouse mutation: altered hair cycle, follicular dystrophy, phenotypic maintenance of skin grafts, and changes in keratin expression.
J. P. Sundberg,M. H. Rourk,Dawnalyn Boggess,Margaret E. Hogan,Beth A. Sundberg,A. P. Bertolino +5 more
TL;DR: The angora mutation provides another useful mouse model for studying the hair cycle and its modulation and was maintained in skin grafted onto C.B-17/Sz-scid/scid mice that had normal pelage hairs and hair cycles, suggesting that circulating or diffusible humoral factors regulating the mouse hair cycle are not involved in this mutation.
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•Journal Article
Harlequin ichthyosis (ichq): a juvenile lethal mouse mutation with ichthyosiform dermatitis.
John P. Sundberg,Dawnalyn Boggess,Margaret E. Hogan,Beth A. Sundberg,M. H. Rourk,B. Harris,K. Johnson,R. W. Dunstan,M. T. Davisson +8 more
TL;DR: The harlequin ichthyosis mouse mutation is very similar to human type 2 harlequins, for which it may be a good model, and skin grafts from harrequin ICHthyosis mice grafted onto immunodeficient nude mice maintained the phenotype for the 10-week observation period.
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Lanceolate hair (lah): a recessive mouse mutation with alopecia and abnormal hair.
Xavier Montagutelli,Margaret E. Hogan,Geneviève Aubin,Alexis Lalouette,Jean Louis Guénet,Lloyd E. King,John P. Sundberg +6 more
TL;DR: A new autosomal recessive mutation of the house mouse developed generalized alopecia associated with breakage of abnormal hair shafts, named 'lanceolate hair' (symbol: lah), which has been localized to the centromeric end of mouse Chromosome 18.
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Cutaneous ultrastructural features of the flaky skin (fsn) mouse mutation.
Katsuko Morita,Margaret E. Hogan,Lillian B. Nanney,Lloyd E. King,Motomu Manabe,Tung-Tien Sun,John P. Sundberg +6 more
TL;DR: The theory that the flaky skin mouse mutation is a naturally occurring analog to one variety of human psoriasis vulgaris is supported.
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