Margaret E. Chen
Brigham and Women's Hospital
6 Papers
7 Citations
Margaret E. Chen is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Renal replacement therapy & Medicine. The author has an hindex of 4, co-authored 5 publications.
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Papers
The Prognostic Value of Histopathologic Lesions in Native Kidney Biopsy Specimens: Results from the Boston Kidney Biopsy Cohort Study.
Anand Srivastava,Ragnar Palsson,Arnaud D. Kaze,Margaret E. Chen,Polly Palacios,Venkata S. Sabbisetti,Rebecca A. Betensky,Theodore I. Steinman,Ravi Thadhani,Ravi Thadhani,Gearoid M. McMahon,Isaac E. Stillman,Helmut G. Rennke,Sushrut S. Waikar +13 more
TL;DR: Across a diverse group of kidney diseases, histopathologic lesions on kidney biopsy provide prognostic information, even after adjustment for proteinuria and eGFR.
172
Kisspeptin Overcomes GnRH Neuronal Suppression Secondary to Hyperprolactinemia in Humans
Katerina Hoskova,Nora Kayton Bryant,Margaret E. Chen,Lisa B. Nachtigall,Margaret F. Lippincott,Ravi Balasubramanian,Stephanie B. Seminara +6 more
TL;DR: Kisspeptin is capable of stimulating hypothalamic GnRH-induced LH pulses in the setting of hyperprolactinemia, and this work found that 73% of subjects exhibited an LH pulse within 30 minutes of first kisspeptin dose.
24
Acute kidney injury after cytoreductive surgery and hyperthermic intraoperative cisplatin chemotherapy for malignant pleural mesothelioma
Tammy Hod,Katherin J. Freedberg,Shveta S. Motwani,Shveta S. Motwani,Margaret E. Chen,Gyorgy Frendl,David E. Leaf,Shruti Gupta,Suraj Sarvode Mothi,William G. Richards,Raphael Bueno,Sushrut S. Waikar,Sushrut S. Waikar +12 more
TL;DR: Acute kidney injury is common after cytoreductive surgery with hyperthermic intraoperative chemotherapy with cisplatin and is associated with poor long-term outcomes and strategies to prevent postoperative acute kidney injury are needed to improve multimodal treatment of malignant pleural mesothelioma.
21
Uric Acid and Acute Kidney Injury in the Critically Ill
Anand Srivastava,Anand Srivastava,Ragnar Palsson,David E. Leaf,Angelica Higuera,Margaret E. Chen,Polly Palacios,Rebecca M. Baron,Venkata S. Sabbisetti,Andrew N. Hoofnagle,Sucheta M. Vaingankar,Paul M. Palevsky,Sushrut S. Waikar +12 more
- 01 Jan 2019
TL;DR: Plasma uric acid levels upon ICU admission or before RRT initiation are not independently associated with adverse clinical outcomes in critically ill patients and this association was confounded by serum creatinine level.
10
Fibroblast Growth Factor 23 Levels Associate with AKI and Death in Critical Illness
David E. Leaf,Kirolos A. Jacob,Anand Srivastava,Margaret E. Chen,Marta Christov,Marta Christov,Harald Jüppner,Venkata S. Sabbisetti,Aline Martin,Myles Wolf,Sushrut S. Waikar +10 more
TL;DR: Elevated FGF23 levels measured in the urine or plasma may be a promising novel biomarker of AKI, death, and other adverse outcomes in critically ill patients.