Marek Droździk
Pomeranian Medical University
113 Papers
408 Citations
Marek Droździk is an academic researcher from Pomeranian Medical University. The author has contributed to research in topics: Transplantation & Medicine. The author has an hindex of 26, co-authored 113 publications. Previous affiliations of Marek Droździk include New York Academy of Medicine.
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Papers
Polymorphism in the P-glycoprotein drug transporter MDR1 gene: a possible link between environmental and genetic factors in Parkinson's disease.
Marek Droździk,Monika Białecka,Katarzyna Myśliwiec,Krystyna Honczarenko,Jan Stankiewicz,Zbigniew Sych +5 more
TL;DR: It appears that mutation of the MDR1 gene predisposes to damaging effects of pesticides, and possibly other toxic xenobiotics transported by P-glycoprotein, leading to Parkinson's disease.
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Activity of essential phospholipids (EPL) from soybean in liver diseases
TL;DR: The available studies characterize EPL as evidence-based medicine, although further long-term controlled clinical trials are required to precisely determine its benefit for alleviating symptoms, improving well-being, inducing histological changes and slowing the progression of liver disease.
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Association of COMT, MTHFR, and SLC19A1(RFC-1) polymorphisms with homocysteine blood levels and cognitive impairment in Parkinson's disease.
Monika Białecka,Mateusz Kurzawski,Anna Roszmann,Piotr Robowski,Emilia J. Sitek,Krystyna Honczarenko,Agnieszka Gorzkowska,Sławomir Budrewicz,Monika Mak,Monika Jarosz,Monika Gołąb-Janowska,Ewa Koziorowska-Gawron,Marek Droździk,Jarosław Sławek +13 more
TL;DR: Age and Hcy plasma levels were found to be independent risk factors predisposing individuals to PD dementia, and polymorphisms in genes related to Hcy metabolism, such as COMT, MTHFR, and SLC19A1(RFC-1).
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•Journal Article
Frequency of common MDR1 gene variants in a Polish population.
TL;DR: The frequencies of common functional polymorphisms in MDR1 gene (2677G > A,T and 3435C > T) were evaluated using PCR-RFLP and allele-specific amplification, in a group of 204 healthy individuals of Caucasian origin from Poland.
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Expression of genes involved in xenobiotic metabolism and transport in end-stage liver disease: up-regulation of ABCC4 and CYP1B1
Mateusz Kurzawski,Violetta Dziedziejko,Mariola Post,Maciej Wójcicki,Elżbieta Urasińska,Janusz Miętkiewski,Marek Droździk +6 more
TL;DR: The study confirmed that the expression of most phase I enzymes is suppressed in end-stage liver disease, and is correlated with a decrease in NR1I2 andNR1I3, the main regulators of xenobiotic metabolism.
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