Marcus Bode

TL;DR: It is found that transcriptome and proteome levels of function as well as the topological organization of synaptic protein clusters, detected by toponomics at physiological sites of hippocampus CA3 region, are all largely conserved between different mice.

TL;DR: A lead target protein in tumor cells that controls cell polarization as a mechanism that is fundamental for migration and metastasis formation has been uncovered, and new functional territories in the CNS defined by high-dimensional synaptic protein clusters have been unveiled.

TL;DR: The Toponome Imaging System (TIS) is the latest development in automated multidimensional fluorescence microscopy capable of imaging over 100 different molecular components in a single cell or tissue section at continuous intensity levels for the first time.

TL;DR: A neural cell detection system for the automatic quantitation of fluorescent lymphocytes in tissue sections was used to analyze CD26 expression in muscle-invasive T-cells and finds highly unusual phenotypes characterized by differential combination of seven cell surface receptors usually involved in co-stimulatory events in T-lymphocytes.