Nephrocystin (NPHP1), the gene for nephronophthisis type 1, is a protein featuring a coiled-coil domain [1]. The coiled coil is a common structural motif formed by 3–5% of all amino acids in proteins [2]. Nowadays, it is vital that busy nephrologists know such things. We recently were faced with a nephrological process that also relied on coiled domains, a more common occurrence but never before described for this purpose.

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Coiled-coiled domains as a mechanism to stop haemorrhage after renal biopsies

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Coiled-coiled domains as a mechanism to stop haemorrhage after renal biopsies