Marcelle Bernstein
8 Papers
11 Citations
Marcelle Bernstein is an academic researcher. The author has contributed to research in topics: Lumpectomy & Radiation therapy. The author has an hindex of 3, co-authored 5 publications.
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Papers
Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial
Jayant S. Vaidya,Max Bulsara,Michael Baum,Frederik Wenz,Samuele Massarut,Steffi Pigorsch,Michael Alvarado,Michael Douek,Christobel Saunders,Henrik Flyger,W. Eiermann,Chris Brew-Graves,Norman R. Williams,Ingrid Potyka,Nicholas Roberts,Marcelle Bernstein,Douglas Brown,Elena Sperk,Siobhan Laws,Marc Sütterlin,Tammy Corica,Steinar Lundgren,Dennis R. Holmes,Lorenzo Vinante,Fernando Bozza,Montserrat Pazos,Magali Le Blanc-Onfroy,Günther Gruber,Wojciech Polkowski,Konstantin J. Dedes,Marcus Niewald,Jens Uwe Blohmer,David R. McCready,Richard A. Hoefer,Pond R. Kelemen,Gloria Petralia,Mary Falzon,David Joseph,Jeffrey S Tobias +38 more
TL;DR: For patients with early breast cancer who met the trial selection criteria, risk adapted immediate single dose TARGIT-IORT during lumpectomy was an effective alternative to EBRT, with comparable long term efficacy for cancer control and lower non-breast cancer mortality.
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Effect of Delayed Targeted Intraoperative Radiotherapy vs Whole-Breast Radiotherapy on Local Recurrence and Survival: Long-term Results From the TARGIT-A Randomized Clinical Trial in Early Breast Cancer
Jayant S. Vaidya,Max Bulsara,Max Bulsara,Christobel Saunders,Henrik Flyger,Jeffrey S Tobias,Tammy Corica,Samuele Massarut,Frederik Wenz,Steffi Pigorsch,Michael Alvarado,Michael Douek,W. Eiermann,Chris Brew-Graves,Norman R. Williams,Ingrid Potyka,Nicholas Roberts,Marcelle Bernstein,Douglas Brown,Elena Sperk,Siobhan Laws,Marc Sütterlin,Steinar Lundgren,Dennis R. Holmes,Lorenzo Vinante,Fernando Bozza,Montserrat Pazos,Magali Le Blanc-Onfroy,Günther Gruber,Wojciech Polkowski,Konstantin J. Dedes,Marcus Niewald,Jens Uwe Blohmer,David R. McCready,Richard A. Hoefer,Pond R. Kelemen,Gloria Petralia,Mary Falzon,Michael Baum,David Joseph +39 more
TL;DR: For early breast cancer, delayed second-procedure single-dose TARGIT-IORT given by reopening the lumpectomy wound had similar long-term mastectomy-free and overall survival compared with EBRT despite higher local recurrence.
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New clinical and biological insights from the international TARGIT-A randomised trial of targeted intraoperative radiotherapy during lumpectomy for breast cancer
Jayant S. Vaidya,Max Bulsara,Michael Baum,Frederik Wenz,Samuele Massarut,Steffi Pigorsch,Michael Alvarado,Michael Douek,Christobel Saunders,Henrik Flyger,W. Eiermann,Chris Brew-Graves,Norman R. Williams,Ingrid Potyka,Nicholas Roberts,Marcelle Bernstein,Douglas Brown,Elena Sperk,Siobhan Laws,Marc Sütterlin,Tammy Corica,Steinar Lundgren,Dennis R. Holmes,Lorenzo Vinante,Fernando Bozza,Montserrat Pazos,Magali Le Blanc-Onfroy,Günther Gruber,Wojciech Polkowski,Konstantin J. Dedes,Marcus Niewald,Jens Uwe Blohmer,David McReady,Richard A. Hoefer,Pond R. Kelemen,Gloria Petralia,Mary Falzon,David Joseph,Jeffrey S Tobias +38 more
TL;DR: The TARGIT-A trial reported risk-adapted targeted intraoperative radiotherapy (TARMIT-IORT) during lumpectomy for breast cancer to be as effective as EBRT as mentioned in this paper.
The TARGIT-A randomised trial -TARGIT-IORT vs whole breast radiotherapy: long term local control and survival.
Jayant S. Vaidya,Max Bulsara,F. Wenz,Elena Sperk,Samuele Massarut,Michael Alvarado,Norman R. Williams,Chris Brew-Graves,Marcelle Bernstein,Dennis Holmes,Lorenzo Vinante,Steffi Pigorsch,Steiner Lundgren,Valery Uhl,David Joseph,Jeffrey S Tobias +15 more
TL;DR: In this article , a single-dose targeted intraoperative radiation therapy (TARGIT-IORT) during lumpectomy for patients with early breast cancer can avoid the inconvenience and toxicity of whole breast radiation therapy and results in reduced pain, a better quality of life, and less traveling by the patient.