Marc Loyens
Lille University of Science and Technology
23 Papers
416 Citations
Marc Loyens is an academic researcher from Lille University of Science and Technology. The author has contributed to research in topics: Trypanosoma cruzi & Antigen. The author has an hindex of 15, co-authored 23 publications. Previous affiliations of Marc Loyens include Pasteur Institute.
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Papers
Interleukin-16 (IL-16) Inhibits Human Immunodeficiency Virus Replication in Cells from Infected Subjects, and Serum IL-16 Levels Drop with Disease Progression
Corinne Amiel,Edith Darcissac,Marie-José Truong,Joëlle Dewulf,Marc Loyens,Yves Mouton,André Capron,George M. Bahr +7 more
TL;DR: Analysis of serum samples from HIV-1-infected subjects over a period of 8 years showed maintained or even increased IL-16 levels during the whole asymptomatic phase and a significant drop on progression to disease.
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Trypanosoma cruzi elongation factor 1-α: nuclear localization in parasites undergoing apoptosis
TL;DR: Indirect immunofluorescence technique and treatment of parasites with the antibiotic drug geneticin which induces the death of epimastigotes by apoptosis showed selective localization of EF-1 alpha in the nucleus of dying parasites, which supports the notion already reported in the case of mammalian cells that EF- 1 alpha could participate in the transcription processes.
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•Journal Article
Trypanosoma cruzi: immunity-induced in mice and rats by trypomastigote excretory-secretory antigens and identification of a peptide sequence containing a T cell epitope with protective activity.
A. Taibi,B. Plumas-Marty,A Guevara-Espinoza,R. Schöneck,H. Pessoa,Marc Loyens,R Piras,T Aguirre,Hélène Gras-Masse,M Bossus +9 more
TL;DR: Analysis of T cell proliferation in response to OVA-coupled peptides clearly indicated that only the 109 to 124 peptide had the capacity to induce the proliferation of T cells from peptide-immunized mice, whereas the percent survival in the control groups was around 16%.
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Cloning and sequencing of a 24-kDa Trypanosoma cruzi specific antigen released in association with membrane vesicles and defined by a monoclonal antibody.
Ali Ouaissi,Tania Aguirre,B. Plumas-Marty,Marta M. Piras,Ralph Schöneck,Hélène Gras-Masse,A. Taibi,Marc Loyens,André Tartar,André Capron,Romano Piras +10 more
TL;DR: The immunoelectron microscopy allowed us to show that the antigen(s) carrying the epitope reacting with mAb Tcr7 is (are) released in association with membrane vesicles which protruded from the parasite surface and the flagellar pocket, likely to be independent of phospholipase C‐mediated release of GPI‐anchored molecules.
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Growth inhibition of Trypanosoma cruzi and Leishmania donovani infantum by different snake venoms: preliminary identification of proteins from Cerastes cerastes venom which interact with the parasites.
Rodolfo Fernandez-Gomez,Halim Zerrouk,Fatima Sebti,Marc Loyens,Abdallah Benslimane,M. Ali Ouaissi +5 more
TL;DR: Venom from three different snake species was tested in vitro against the protozoan parasites Trypanosoma cruzi and Leishmania donovani infantum, and preliminary identification of components which interact preferentially with the pathogens was allowed.
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