Marc J. M. Bonten
Utrecht University
664 Papers
2.8K Citations
Marc J. M. Bonten is an academic researcher from Utrecht University. The author has contributed to research in topics: Medicine & Intensive care. The author has an hindex of 88, co-authored 600 publications. Previous affiliations of Marc J. M. Bonten include University Medical Center Utrecht & Oklahoma State University Center for Health Sciences.
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Papers
Colonization pressure: a critical parameter in the epidemiology of antibiotic-resistant bacteria
TL;DR: The recognition of colonization pressure as an important risk factor for acquisition of antibiotic-resistant bacteria in the ICU, including Acinetobacter species, has major consequences for the understanding of risk factor analyses.
Oral Decontamination with Chlorhexidine Reduces the Incidence of Ventilator-associated Pneumonia
Mirelle Koeman,André van der Ven,Eelko Hak,Hans C. A. Joore,Karin A H Kaasjager,Anne Marie G. A. de Smet,Graham Ramsay,Tom Dormans,Leon P. H. J. Aarts,Ernst E. de Bel,Willem N. M. Hustinx,Ingeborg van der Tweel,Andy I. M. Hoepelman,Marc J. M. Bonten +13 more
TL;DR: Topical oral decontamination with CHX or CHX/COL reduces the incidence of VAP and provides significant reduction in oropharyngeal colonization with both gram-negative and gram-positive microorganisms, whereas CHX mostly affected gram- positive microorganisms.
Validation of a novel surveillance paradigm for ventilator-associated events
Peter M. C. Klein Klouwenberg,Maaike S. M. van Mourik,David S. Y. Ong,Janneke Horn,Marcus J. Schultz,Olaf L. Cremer,Marc J. M. Bonten +6 more
TL;DR: P1 Validation of a novel surveillance paradigm for ventilator-associated events for Critical Care 2013 is validation.
Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island
Willem van Schaik,Janetta Top,David R. Riley,Jos Boekhorst,Joyce E. P. Vrijenhoek,Claudia M. E. Schapendonk,Antoni P. A. Hendrickx,Antoni P. A. Hendrickx,Isaac J. Nijman,Marc J. M. Bonten,Hervé Tettelin,Rob J. L. Willems +11 more
TL;DR: Genes involved in environmental persistence, colonization and virulence can easily be aquired by E. faecium, which will make the development of successful treatment strategies targeted against this organism a challenge for years to come.
Cytomegalovirus seroprevalence as a risk factor for poor outcome in acute respiratory distress syndrome
David S. Y. Ong,Peter M. C. Klein Klouwenberg,Frans M. Verduyn Lunel,Cristian Spitoni,Jos F. Frencken,Huberta A. T. Dekker,Marcus J. Schultz,Marc J. M. Bonten,Olaf L. Cremer +8 more
TL;DR: Cytomegalovirus seroprevalence is not associated with prolonged mechanical ventilation or increased mortality in critically ill patients with acute respiratory distress syndrome, with possible exception of patients presenting with septic shock.