Marc Barthold
Hannover Medical School
9 Papers
114 Citations
Marc Barthold is an academic researcher from Hannover Medical School. The author has contributed to research in topics: Liver transplantation & Transplantation. The author has an hindex of 8, co-authored 9 publications.
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Papers
Hepatocyte transplantation in an acute liver failure due to mushroom poisoning.
Andrea L.C. Schneider,Masoumeh Attaran,Peter N. Meier,Christian P. Strassburg,Michael P. Manns,Michael Ott,Marc Barthold,Lubomir Arseniev,Thomas Becker,Bernd Panning +9 more
TL;DR: 1. Oral involvement in chronic graft versus host disease following allogeneic bone marrow transplantation, and successful treatment or Oral lichen planus like chronic graft-versus-host-disease with topical tacrolimus.
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Large-scale isolation of human hepatocytes for therapeutic application.
Krassimira Alexandrova,Carsten Griesel,Marc Barthold,Hans-Gert Heuft,Michael Ott,Michael Winkler,Harald Schrem,Michael P. Manns,Timm Bredehorn,Marc Net,Martí Manyalich I Vidal,Sabine Kafert-Kasting,Lubomir Arseniev +12 more
TL;DR: A standardized and cGMP conform method of hepatocyte isolation from nontransplantable liver organs was established, which reproducibly yields large amounts of hepatocytes suitable for therapeutic application.
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Rapid generation of clinical-grade antiviral T cells: selection of suitable T-cell donors and GMP-compliant manufacturing of antiviral T cells
Sabine Tischer,Christoph Priesner,Hans-Gert Heuft,Lilia Goudeva,Wolfgang Mende,Marc Barthold,Stephan Kloeß,Lubomir Arseniev,Krasimira Aleksandrova,Britta Maecker-Kolhoff,Rainer Blasczyk,Ulrike Koehl,Britta Eiz-Vesper +12 more
TL;DR: The generation of antiviral CD4+ and CD8+ T cells by CliniMACS CCS can be extended to a broad spectrum of common pathogen-derived peptide pools in single or multiple applications to facilitate and enhance the efficacy of adoptive T-cell immunotherapy.
Enzyme induction in cryopreserved human hepatocyte cultures.
Sabine Kafert-Kasting,Krassimira Alexandrova,Marc Barthold,Britta Laube,Gerhard Friedrich,Lubomir Arseniev,Jan G. Hengstler +6 more
TL;DR: Human hepatocytes cryopreserved on collagen gels show a clear induction of CYP3A4 by rifampicin, although the basal activities are reduced compared to non-frozen cells.
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Liver cell transplantation: basic investigations for safe application in infants and small children.
Jochen Meyburg,Krassimira Alexandrova,Marc Barthold,Sabine Kafert-Kasting,Andrea Schneider,Masoumeh Attaran,Friederike Hoerster,Jan Schmidt,Georg F. Hoffmann,Michael Ott +9 more
TL;DR: A mathematical model is developed to estimate total hepatocyte counts in relation to bodyweight to make possible more appropriate dose calculations and concludes that especially with the use of small catheters, human LCT should be safe and efficient even in small infants and neonates.
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