Manuela Simonato
University of Padua
53 Papers
91 Citations
Manuela Simonato is an academic researcher from University of Padua. The author has contributed to research in topics: Medicine & Cardiopulmonary bypass. The author has an hindex of 11, co-authored 40 publications.
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Papers
Dosing of porcine surfactant: effect on kinetics and gas exchange in respiratory distress syndrome.
Paola Cogo,Maddalena Facco,Manuela Simonato,Giovanna Verlato,Clementina Rondina,Aldo Baritussio,Gianna Toffolo,Virgilio P. Carnielli +7 more
TL;DR: Porcine surfactant given to preterm infants with RDS at a dose of 200 mg/kg resulted in a longer DSPC half-life, fewer retreatments, and better oxygenation index values.
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Pharmacokinetics and clinical predictors of surfactant redosing in respiratory distress syndrome
Paola Cogo,Maddalena Facco,Manuela Simonato,Daniele De Luca,Francesca De Terlizi,Umberto Rizzotti,Giovanna Verlato,Maria Paola Bellagamba,Virgilio P. Carnielli +8 more
TL;DR: When optimizing surfactant replacement therapy and its cost–benefit ratio, pharmacokinetics and clinical variables associated with need of redosing should be taken into account.
Tryptophan Metabolites, Cytokines, and Fatty Acid Binding Protein 2 in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Manuela Simonato,Stefano Dall'Acqua,Caterina Zilli,Stefania Sut,Romano Tenconi,Nicoletta Gallo,Paolo Sfriso,Leonardo Sartori,Francesco Cavallin,Ugo Fiocco,Paola Cogo,Paolo Agostinis,Anna Aldovini,Daniela Bruttomesso,Renzo Marcolongo,Stefano Comai,Aldo Baritussio +16 more
TL;DR: In this article, the authors investigated clinical and biochemical traits in 40 ME/CFS patients and 40 sex-and age-matched healthy controls and found that patients with the start of the disease after infection showed lower levels of kynurenine (p = 0.034) than those not starting after an infection.
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Disaturated-phosphatidylcholine and Surfactant protein-B turnover in human acute lung injury and in control patients
Manuela Simonato,Aldo Baritussio,Carlo Ori,Luca Vedovelli,Sandra Rossi,Lorenza Dalla Massara,Sabina Rizzi,Virgilio P. Carnielli,Paola Cogo +8 more
TL;DR: Surfactant protein-B turned over at faster rate than disaturated-phosphatidylcholine both in ARDS/ALI patients and in controls, and the synthesis of these two surfactant components may be differently regulated.
Impaired surfactant protein B synthesis in infants with congenital diaphragmatic hernia
Paola Cogo,Manuela Simonato,Olivier Danhaive,Olivier Danhaive,Giovanna Verlato,Giovanna Cobellis,Francesco Savignoni,Donatella Peca,Aldo Baritussio,Virgilio P. Carnielli +9 more
TL;DR: In infants with CDH, SP-B fractional synthesis rate and amount were 62±27% and 57±22% lower, respectively, than the value found in infants without lung disease, and there were no significant group differences in DSPC fractional syntheses.
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