Mantelingu Kempegowda
University of Mysore
13 Papers
28 Citations
Mantelingu Kempegowda is an academic researcher from University of Mysore. The author has contributed to research in topics: Chemistry & Non-homologous end joining. The author has an hindex of 3, co-authored 10 publications.
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Papers
Structural studies of 2,5-disubstituted 1,3,4-thiadiazole derivatives from dithioesters under the mild condition: Studies on antioxidant, antimicrobial activities, and molecular docking
Kemparaje Gowda,Hassan A. Swarup,Sandhya C. Nagarakere,Shobith Rangappa,Rangappa S. Kanchugarkoppal,Mantelingu Kempegowda +5 more
TL;DR: The results of antioxidant activity studies revealed that compound 4k manifested profound antioxidant potential, which indicates that 4k possess excellent antibacterial and antioxidant activity.
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Water-soluble version of SCR7-pyrazine inhibits DNA repair and abrogates tumor cell proliferation
Monica Pandey,Vidya Gopalakrishnan,Hassan A. Swarup,Sujeet Kumar,Radha Gudapureddy,Anjana Elizabeth Jose,Supriya V. Vartak,Robin Sebastian,Mrinal Srivastava,Bibha Choudhary,Mantelingu Kempegowda,Subhas S. Karki,Sathees C. Raghavan +12 more
- 01 Jan 2019
TL;DR: The results suggest that Na-SCR7-P can target NHEJ and other DNA repair pathways by disrupting Ligase mediated joining and can potentially be used as a strategy for cancer treatment, owing to its water solubility.
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An efficient synthesis of medicinally important indole based triarylmethanes by using propylphosphonic anhydride (T3P
Srinivas Cheruku,Chaithra Nagaraju,Poornima Shetty,Swarup Hassan A,Sandhya Nagarakere C,Kumara Manikyanally N,Mantelingu Kempegowda +6 more
TL;DR: In this paper, an economical and efficient method for the synthesis of medicinally and synthetically important indole-based triarylmethanes by using indoles and benzhydrols in the presence of pr...
10
SCR7, an inhibitor of NHEJ can sensitize tumor cells to ionization radiation.
Vidya Gopalakrishnan,Vidya Gopalakrishnan,Shivangi Sharma,Ujjayinee Ray,Meghana Manjunath,Divya Lakshmanan,Supriya V. Vartak,Vindya K. Gopinatha,Mrinal Srivastava,Mrinal Srivastava,Mantelingu Kempegowda,Bibha Choudhary,Sathees C. Raghavan +12 more
TL;DR: In this article, a small molecule inhibitor, SCR7, which inhibited NHEJ in a DNA Ligase IV dependent manner, was reported to potentiate the effect of γ-radiation (IR) that induces DNA breaks as intermediates to eradicate cancer cells.
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Rapid and Selective Spectrophotometric Assay for Micromolar Level Determination of Hydrogen Peroxide Based on Biocatalysis of Horseradish Peroxidase
TL;DR: The use of hydrogen peroxide (H2O2) is an essential compound in food, pharmaceutical, clinical, industrial, and environmental analysis as mentioned in this paper, and has been widely used for preservation of raw milk due to its bacteri...
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