Mangmang Li
Chinese Academy of Sciences
14 Papers
58 Citations
Mangmang Li is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Tobacco mosaic virus & Embryonic stem cell. The author has an hindex of 8, co-authored 12 publications.
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Papers
Distinct Regulatory Mechanisms and Functions for p53-Activated and p53-Repressed DNA Damage Response Genes in Embryonic Stem Cells
TL;DR: A whole-genome study of p53-mediated DNA damage signaling in mouse ES cells supports a model where, in response to DNA damage, p53 affects the status of ES cells through activating differentiation-associated genes and repressing ES cell-enriched genes.
284
A modified TMV-based vector facilitates the expression of longer foreign epitopes in tobacco ☆
Lubin Jiang,Qiaoli Li,Mangmang Li,Zhiai Zhou,Ligang Wu,Jihua Fan,Qingqi Zhang,Huihui Zhu,Zhengkai Xu,Zhengkai Xu +9 more
TL;DR: The new TMV-based vector developed in which four to six C-terminal amino acid residues were deleted from the viral coat protein (CP) subunit may meet the requirement of expressing longer foreign peptides for different vaccines and other medicines.
49
Morphology and stability changes of recombinant TMV particles caused by a cysteine residue in the foreign peptide fused to the coat protein.
TL;DR: In the studies of expressing various foreign peptides using a TMV-based vector, a portion of morphologically altered progeny viral particles from some recombinant TMV constructs were detected in the first systematically infected upper leaves, but not in the fully expanded inoculated leaves, from infected tobacco plants.
19
Genome-wide studies of the transcriptional regulation by p53
TL;DR: A mini-review summarizes recent progress in studying the tumor suppressive functions of p53 using genome-wide approaches, and offers some perspectives on this rapidly expanding field.
13
Elevating CLIC4 in Multiple Cell Types Reveals a TGF- Dependent Induction of a Dominant Negative Smad7 Splice Variant.
Anjali Shukla,Yihan Yang,Sara Madanikia,Yan Ho,Mangmang Li,Vanesa Roxana Sánchez,Christophe Cataisson,Jing Huang,Stuart H. Yuspa +8 more
TL;DR: It is reported that elevated CLIC4 alters Smad7 function, a feedback inhibitor of the TGF-β pathway, and this discovery adds another dimension to the myriad ways by which CLIC 4 modifies T GF-β signaling.