Man Zhang
China Three Gorges University
7 Papers
2 Citations
Man Zhang is an academic researcher from China Three Gorges University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 2 publications.
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Papers
Long noncoding RNA TUG1 promotes renal cell carcinoma cell proliferation, migration and invasion by downregulating microRNA‑196a.
TL;DR: It is demonstrated that lncRNA‑TUG1 was able to promote RCC cell proliferation, migration and invasion in vitro by suppressing miR‑196a, and proposed a novel potential therapeutic target, the lnc RNA‑Tug1‑miR‐196a axis, which may be applicable to the treatment of RCC.
The prognostic value and clinical significance of mitophagy-related genes in hepatocellular carcinoma
Wei Xu,Dongxu Zhao,Xiaowei Huang,Man Zhang,Minyue Yin,Lu Liu,Hongyu Wu,Zhen Weng,Chunfang Xu +8 more
TL;DR: The prognostic model demonstrated high reliability, indicating that it could accurately predict the prognosis of HCC patients, and it was discovered that typical HCC treatment medicines had varying impacts on patients classification as high or low risk, and that individuals classified as high risk are more likely to fail immunotherapy.
14
Molecular mechanisms of pancreatic cancer liver metastasis: the role of PAK2
Hao Yang,Wenxia Wang,Jing Zhang,Dongxu Zhao,Man Zhang,Wenxin Zhu,Chunfang Xu +6 more
TL;DR: PAK2 emerged as a pivotal gene orchestrating pancreatic cancer liver metastasis and facilitated the angiogenic potential of cancer cells and promotes the epithelial-mesenchymal transition process by activating the TGF-beta signaling pathway.
11
Unveiling the role of regulatory T cells in the tumor microenvironment of pancreatic cancer through single-cell transcriptomics and in vitro experiments
Wei Xu,Wenjia Zhang,Dongxu Zhao,Qi Wang,Man Zhang,Qiang Li,Wenxin Zhu,Chunfang Xu +7 more
TL;DR: Treg cells played a crucial role in the pancreatic cancer microenvironment, and their presence held a dual significance, which was vital for understanding the limitations of Treg cell-targeted therapies.
7
Significance of monocyte infiltration in patients with gastric cancer: A combined study based on single cell sequencing and TCGA
TL;DR: Based on single cell sequencing data, Wang et al. as discussed by the authors conducted a detailed analysis of gastric cancer patients and normal tissues to determine the role of monocytes in the progression of Gastric cancer.