Mamoru Shimada
Osaka University
21 Papers
154 Citations
Mamoru Shimada is an academic researcher from Osaka University. The author has contributed to research in topics: Medicine & Gene. The author has an hindex of 6, co-authored 21 publications. Previous affiliations of Mamoru Shimada include Kōchi University.
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Papers
Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes.
TL;DR: Human counterpart of yeast PMS1 genes is isolated and analyzed, indicating that human PMS genes constituted a multiple gene family and that some of the family members have been mapped to chromosomal bands 7q11.23 and 7q22 by fluorescent in situ hybridization.
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Obesity as a risk factor for GERD in Japan.
Masahiro Sakaguchi,Hiroshi Oka,Takashi Hashimoto,Yutaka Asakuma,Miyuki Takao,Goki Gon,Makoto Yamamoto,Yoshihisa Tsuji,Norihiko Yamamoto,Mamoru Shimada,Kyowon Lee,Kiyoshi Ashida +11 more
TL;DR: It was concluded that obesity is a risk factor for gastroesophageal reflux disease in Japan and both GERD prevalence and the prevalence of hernia were significantly higher in obese subjects, andThe prevalence of GERD in subjects who had gained weight was also significantly higher.
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K-ras gene mutations and loss of heterozygosity at the p53 gene locus relative to histological characteristics of mucin-producing tumors of the pancreas
Yuzo Sakai,Akio Yanagisawa,Mamoru Shimada,Eiji Hidaka,Makoto Seki,Yurika Tada,Tae Harada,Hiromitsu Saisho,Yo Kato +8 more
TL;DR: Both the K-ras and p53 gene alterations occur in the intraductal stage of MPT, and the latter is superimposed on the former during the course of tumor progression, however, the pattern of association of histological features with genetic alteration differs from tumor to tumor.
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Infrequent Replication Errors at Microsatellite Loci in Tumors of Patients with Multiple Primary Cancers of the Esophagus and Various Other Tissues
Mamoru Shimada,Akira Horii,Shin Sasaki,Akio Yanagisawa,Yo Kato,Kenichi Yamashita,Kazuhiro Okagawa,Keiji Yamasaki,Shingo Ishiguro,Masatoshi Inoue,Hitoshi Shiozaki,Yusuke Nakamura +11 more
TL;DR: It is noteworthy that a single patient who developed multiple cancers revealed RER(+) phenotypes at multiple microsatellite loci in both tumors, indicating that a defect in the DNA repair gene(s) may have played an important role in the development of the tumors in this patient.
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Long-term outcomes of standardized colonic stenting using WallFlex as a bridge to surgery: Multicenter prospective cohort study.
Toshio Kuwai,Yuzuru Tamaru,Ryusaku Kusunoki,Shuntaro Yoshida,Takeaki Matsuzawa,Hiroyuki Isayama,Iruru Maetani,Mamoru Shimada,Tomonori Yamada,Shuji Saito,Masafumi Tomita,Koichi Koizumi,Toshiyasu Shiratori,Toshiyuki Enomoto,Yoshihisa Saida +14 more
TL;DR: In this article, the authors investigated the long-term outcomes of BTS colonic stenting using standardized SEMS placement and found that the SEMS insertion technique achieved high technical success and low perforation rate.
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