Malini Chinta
Stanford University
30 Papers
7 Citations
Malini Chinta is an academic researcher from Stanford University. The author has contributed to research in topics: Medicine & Wound healing. The author has an hindex of 6, co-authored 13 publications.
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Papers
Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring
Shamik Mascharak,Heather E. desJardins-Park,Michael F. Davitt,Michelle Griffin,Mimi R. Borrelli,Alessandra L. Moore,Kellen Chen,Bryan Duoto,Malini Chinta,Deshka S. Foster,Abra H. Shen,Michael Januszyk,Sun Hyung Kwon,Gerlinde Wernig,Derrick C. Wan,H. Peter Lorenz,Geoffrey C. Gurtner,Michael T. Longaker +17 more
TL;DR: In this paper, the authors identify a dermal ENF subpopulation that gives rise to postnatally derived EPFs by activating Engrailed-1 expression during adult wound healing.
376
Integrated spatial multiomics reveals fibroblast fate during tissue repair.
Deshka S. Foster,Michael Januszyk,Kathryn E. Yost,Malini Chinta,Gunsagar S. Gulati,Alan T. Nguyen,Austin R. Burcham,Ankit Salhotra,R. Chase Ransom,Dominic Henn,Kellen Chen,Shamik Mascharak,Karen Tolentino,Ashley L. Titan,R. Ellen Jones,Oscar Silva,W. Tripp Leavitt,Clement D. Marshall,Heather E. Des Jardins-Park,Michael S. Hu,Derrick C. Wan,Gerlinde Wernig,Dhananjay Wagh,John A. Coller,Jeffrey A. Norton,Geoffrey C. Gurtner,Aaron M. Newman,Howard Y. Chang,Michael T. Longaker +28 more
TL;DR: In this paper, a multimodal-omics platform for the comprehensive study of cell populations in complex tissue was presented, which has allowed to characterize the cells involved in wound healing across both time and space.
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Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin.
Deshka S. Foster,Michael Januszyk,Daniel Delitto,Kathryn E. Yost,Michelle Griffin,Jason Guo,Nicholas Guardino,Andrea E. Delitto,Malini Chinta,Austin R. Burcham,Alan T. Nguyen,Khristian E. Bauer-Rowe,Ashley L. Titan,Ankit Salhotra,R. Ellen Jones,Oscar da Silva,Hunter G. Lindsay,Charlotte E. Berry,Kellen Chen,Dominic Henn,Shamik Mascharak,Heather E. Talbott,Alex S. Kim,Fatemeh Nosrati,Dharshan Sivaraj,Ryan C. Ransom,Michael Matthews,Anum Khan,Dhananjay A. Wagh,John Van Coller,Geoffrey C. Gurtner,Derrick C. Wan,Irene Wapnir,Howard Y. Chang,Jeffrey A. Norton,Michael T. Longaker +35 more
TL;DR: In this paper , the authors used paired, same-cell chromatin accessibility and transcriptome analysis to identify three superclusters: steady state-like (SSL), mechanoresponsive (MR), and immunomodulatory (IM) CAFs.
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Pancreatic Cancer Associated Fibroblasts (CAF): Under-Explored Target for Pancreatic Cancer Treatment.
TL;DR: What the authors know about the role of CAFs in pancreatic cancer cell growth, invasion, and metastases are discussed and different strategies that are being and could be explored as anti-CAF treatments for pancreaticcancer are presented.
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The Spectrum of Scarring in Craniofacial Wound Repair.
Heather E. desJardins-Park,Shamik Mascharak,Malini Chinta,Derrick C. Wan,Michael T. Longaker +4 more
TL;DR: The typical wound healing process in both skin and the oral cavity is described and the current state of research into mechanisms of scarless healing is discussed, toward the ultimate goal of achieving scarless adult skin healing.