Makoto Ono
Tokyo Medical and Dental University
21 Papers
182 Citations
Makoto Ono is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Newborn screening & Adrenal insufficiency. The author has an hindex of 9, co-authored 21 publications. Previous affiliations of Makoto Ono include Prince Henry's Institute of Medical Research.
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Papers
Mutation and gene copy number analyses of six pituitary transcription factor genes in 71 patients with combined pituitary hormone deficiency: identification of a single patient with LHX4 deletion.
Sumito Dateki,Maki Fukami,Ayumi Uematsu,Masayuki Kaji,Manami Iso,Makoto Ono,Michiyo Mizota,Susumu Yokoya,Katsuaki Motomura,Eiichi Kinoshita,Hiroyuki Moriuchi,Tsutomu Ogata +11 more
TL;DR: The results imply the rarity of abnormalities affecting the six genes in patients with CPHD and the significance of the gene copy number analysis in such patients.
Newborn screening for congenital adrenal hyperplasia in Tokyo, Japan from 1989 to 2013: a retrospective population-based study
Atsumi Tsuji,Kaoru Konishi,Satomi Hasegawa,Akira Anazawa,Toshikazu Onishi,Makoto Ono,Tomohiro Morio,Teruo Kitagawa,Kenichi Kashimada +8 more
TL;DR: The data suggest that the newborn screening in Tokyo was effective, especially for sex assignment and preventing fatal adrenal crisis, and higher PPV than previous CAH screening studies, which might be due to the use of variable cutoffs according to gestational age and birth weight.
Liquid chromatography–tandem mass spectrometric method for determination of salivary 17α-hydroxyprogesterone: A noninvasive tool for evaluating efficacy of hormone replacement therapy in congenital adrenal hyperplasia
Yujin Shibayama,Tatsuya Higashi,Kazutake Shimada,Ken ichi Kashimada,Toshikazu Onishi,Makoto Ono,Kentaro Miyai,Shuki Mizutani +7 more
TL;DR: The result from the salivary 17OHP measurement in patients with congenital adrenal hyperplasia demonstrated that the proposed method is very useful for monitoring of the therapeutic efficacy during hormone replacement therapy.
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Nationwide surveillance of circulatory collapse associated with levothyroxine administration in very-low-birthweight infants in Japan.
Masahiko Kawai,Satoshi Kusuda,Kazutoshi Cho,Reiko Horikawa,Fumihiko Takizawa,Makoto Ono,Tetsuo Hattori,Makoto Oshiro +7 more
TL;DR: This study was performed to investigate the incidence of LCC associated with the administration of LT4 to VLBW infants and found no significant differences in the number of cases or severity of cases reported.
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Knockdown of XAB2 enhances all-trans retinoic acid-induced cellular differentiation in all-trans retinoic acid-sensitive and -resistant cancer cells.
Kumiko Ohnuma-Ishikawa,Tomohiro Morio,Takayuki Yamada,Yuji Sugawara,Makoto Ono,Masayuki Nagasawa,Akio Yasuda,Chikao Morimoto,Kei Ohnuma,Nam H. Dang,Hajime Hosoi,Eric Verdin,Shuki Mizutani +12 more
TL;DR: The results strongly suggest that XAB2 is a component of the RAR corepressor complex with an inhibitory effect on ATRA-induced cellular differentiation and thatXAB2 plays a role in ATra-mediated cellular differentiation as an important aspect of cancer therapy.
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