Maki Wakamiya
University of Texas Medical Branch
54 Papers
196 Citations
Maki Wakamiya is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 27, co-authored 50 publications. Previous affiliations of Maki Wakamiya include University of Texas MD Anderson Cancer Center & Children's Medical Research Institute.
Chat about Author
Papers
The DNA glycosylase NEIL2 plays a vital role in combating SARS-CoV-2 infection
Tapas K. Hazra,Nisha Tapryal,Anirban Chakraborty,Kempaiah Rayavara,Maki Wakamiya,Azharul Islam,Lang Pan,Jason Hsu,Vivian Tat,Junki Maruyama,Koa Hosoki,Ibrahim M Sayed,J. Alcantara,Vanessa Castillo,Courtney Lynn Tindle,Altaf H. Sarker,Victor J. Cardenas,Gulshan Sharma,Laura Crotty Alexander,Sanjiv Sur,Gourisankar Ghosh,Slobodan Paessler,Debashis Sahoo,Pradipta Ghosh,Soumita Das,Istvan Boldogh,Chien-Te Kent Tseng +26 more
TL;DR: The data suggest that NEIL2 plays a previously unidentified role in regulating CoV-2-induced pathogenesis, via inhibiting viral replication and preventing exacerbated proinflammatory responses, and also via its well-established role of repairing host genome damage.
Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections
Zhengchen Su,Qing Chang,Aleksandra Drelich,Thomas R. Shelite,Barbara M. Judy,Yakun Liu,Jie Xiao,Changchen Zhou,Xi He,Taís Berelli Saito,Shao Jun Tang,Lynn Soong,Maki Wakamiya,Xiang Fang,Alexander Bukreyev,Thomas G. Ksiazek,William K. Russell,Bin Gong +17 more
TL;DR: It is reported that ANxA2-knockout (KO) mice are more susceptible to CMHs in response to rickettsia and Ebola virus infections, suggesting an essential role of ANXA2 in protecting vascular integrity during these intracellular pathogen infections.
Host EPAC1 modulates rickettsial adhesion to vascular endothelial cells via regulation of ANXA2 Y23 phosphorylation
Zhengchen Su,Thomas R. Shelite,Yuan Qiu,Qing Chang,Maki Wakamiya,Jiani Bei,Xi He,Changcheng Zhou,Yakun Liu,Angelo Gaitas,Tais B. Saito,Bin Gong +11 more
TL;DR: In this paper, the role of EPAC1-ANXA2 signaling pathway in the regulation of rickettsial adhesion to ECs was investigated using fluidic force microscopy (FluidFM) and single living brain microvascular EC study.
Exchange protein directly activated by cAMP plays a critical role in regulation of vascular fibrinolysis.
Xi He,Aleksandra Drelich,Shangyi Yu,Qing Chang,Dejun Gong,Yixuan Zhou,Yue Qu,Yang Yuan,Zhengchen Su,Yuan Qiu,Shao Jun Tang,Angelo Gaitas,Thomas G. Ksiazek,Zhi-yun Xu,Jia Zhou,Zongdi Feng,Maki Wakamiya,Fanglin Lu,Bin Gong +18 more
TL;DR: A novel regulatory role for EPAC1 in vascular fibrinolysis is revealed, which regulates the SVEC plasminogen conversion depended on ANXA2 and is found in endocardial tissues beneath atrial mural thrombi in patients.