Mahmoud Reza Jaafari
Mashhad University of Medical Sciences
383 Papers
1.2K Citations
Mahmoud Reza Jaafari is an academic researcher from Mashhad University of Medical Sciences. The author has contributed to research in topics: Liposome & Medicine. The author has an hindex of 46, co-authored 323 publications. Previous affiliations of Mahmoud Reza Jaafari include University of California, San Francisco & University of Saskatchewan.
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Papers
Vaccines targeting angiogenesis in melanoma
Fatemeh Zahedipour,Parvin Zamani,Khadijeh Jamialahmadi,Mahmoud Reza Jaafari,Amirhossein Sahebkar +4 more
TL;DR: In this paper, a review of the potential progress in developing vaccines for targeting melanoma angiogenesis in melanoma is presented, including DNA, peptide, protein, dendritic cell-based, and endothelial cell vaccines.
Immunity Evaluation of an Experimental Designed Nanoliposomal Vaccine Containing FMDV Immunodominant Peptides
L. Heshmati,Seyed Mahdi Rezayat,Seyed Mahdi Rezayat,R. Madani,R. Madani,Tara Emami,Mahmoud Reza Jaafari,F. Golchinfar,M. Kazemi,S. M. Azizmi Dezfouli +9 more
TL;DR: The obtained results indicated that although antibody titer was observed, the amount was lower compared to the groups that received inactivated virus-containing liposomes, and showed that liposome was an appropriate adjuvant, compared to other adjuvants, and can act as a depot and induce an immune response.
Improved anticancer efficacy of epirubicin by magnetic mesoporous silica nanoparticles: in vitro and in vivo studies
TL;DR: The targeted drug delivery through external magnet-attraction using EPI-loaded MMSNs resulted in high tumor cell uptake, which leads to elimination of cancer cells effectively, and targeting with drug-loaded EPI with the aid of external magnetic gradient had significantly higher inhibition efficacy towards tumor growth than the free EPI treated mice.
Anti-ischemic Effect of Nigella sativa L. Seed in Male Rats
TL;DR: Results indicate that the N. sativa seed extracts could have a therapeutic effect against cerebral ischemia and significantly reduced neural cell injuries in the CA1 and CA3 regions of rat hippocampus.
Chitosan Nanoparticles Loaded with Whole and Soluble Leishmania Antigens, and Evaluation of Their Immunogenecity in a Mouse Model of Leishmaniasis.
Mansure Hojatizade,Mahsa Soleymani,Mohsen Tafaghodi,Ali Badiee,Omid Chavoshian,Mahmoud Reza Jaafari +5 more
TL;DR: Nanoparticulate formulations are not suitable candidates for preferential induction of a pure Th1-type immune response and immunization against Leishmania infection, however, it might be a good strategy in other infectious diseases where a mixed Th1/Th2 immune response is required.