Mahmoud Reza Jaafari
Mashhad University of Medical Sciences
383 Papers
1.2K Citations
Mahmoud Reza Jaafari is an academic researcher from Mashhad University of Medical Sciences. The author has contributed to research in topics: Liposome & Medicine. The author has an hindex of 46, co-authored 323 publications. Previous affiliations of Mahmoud Reza Jaafari include University of California, San Francisco & University of Saskatchewan.
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Papers
MicroRNA: A novel target of curcumin in cancer therapy.
Hamed Mirzaei,Aria Masoudifar,Amirhossein Sahebkar,Naser Zare,Javid Sadri Nahand,Bahman Rashidi,Emadodin Mehrabian,Mohsen Mohammadi,Hamid Reza Mirzaei,Mahmoud Reza Jaafari +9 more
TL;DR: In this article, the authors highlighted various miRNAs which could be affected by curcumin in various types of cancer and highlighted exosomes containing curcurumin as suitable therapeutic tools in cancer therapy.
Preparation of nanoliposomes linked to HER2/neu-derived (P5) peptide containing MPL adjuvant as vaccine against breast cancer.
Saeedeh Rastakhiz,Mona Yazdani,Sheida Shariat,Atefeh Arab,Amir Abbas Momtazi-Borojeni,Nastaran Barati,Mercedeh Mansourian,Mohamdreza Amin,Azam Abbasi,Zahra Saberi,Seyed Amir Jalali,Ali Badiee,Mahmoud Reza Jaafari +12 more
TL;DR: The results demonstrated that tumor‐bearing mice immunized with Lip/DOPE/MPL/P5 formulation had the most released interferon‐γ and the highest cytotoxic T lymphocyte responses that led to the lowest tumor size and the longest survival time than those of other formulations.
Immunoregulatory, proliferative and anti-oxidant effects of nanocurcuminoids on adipose-derived mesenchymal stem cells
Forouzan Yousefi,Fahimeh Lavi Arab,Mahmoud Reza Jaafari,Maryam Rastin,Nafiseh Tabasi,Mahdi Hatamipour,Karim Nikkhah,Mahmoud Mahmoudi +7 more
TL;DR: Low concentrations of nanocurcuminoids are beneficial for MSC proliferation, protection of MSCs from apoptosis, reducing inflammatory cytokines and SOD activity and demonstrate that nano-formulation of curcuminoid eliminates these shortcomings.
Improving potency of Nanoliposomal AE36 peptide vaccine by adding CD4+ T cell helper epitope and MPL in TUBO breast cancer mice model
Parvin Zamani,Mohammad Mashreghi,Mahere Rezazade Bazaz,Farshad Mirzavi,Mehdi Barati,Fatemeh Zahedipour,Mahmoud Reza Jaafari +6 more
TL;DR: In this paper , a liposomal-based peptide vaccine composed of AE36 (HER2/neu)-derived peptide and PADRE (Pan HLA-DR peptide) as well as monophosphoryl lipid A (MPLA) adjuvant was evaluated in BALB/c mice breast cancer models bearing TUBO tumors.
Improving anti-tumour efficacy of PEGylated liposomal doxorubicin by dual targeting of tumour cells and tumour endothelial cells using anti-p32 CGKRK peptide.
Mohammad Mashreghi,Mahdi Faal Maleki,Maryam Karimi,Fatemeh Kalalinia,Ali Badiee,Mahmoud Reza Jaafari +5 more
TL;DR: In this paper, the authors surface functionalize PEGylated liposomal doxorubicin (PLD) using anti-p32 CGKRK peptide to evaluate its anti-angiogenic and anti-tumour activities.