Magno Junqueira
Federal University of Rio de Janeiro
57 Papers
431 Citations
Magno Junqueira is an academic researcher from Federal University of Rio de Janeiro. The author has contributed to research in topics: Biology & Proteome. The author has an hindex of 24, co-authored 48 publications. Previous affiliations of Magno Junqueira include National Institute of Standards and Technology & Max Planck Society.
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Papers
A Genome-Scale RNAi Screen for Oct4 Modulators Defines a Role of the Paf1 Complex for Embryonic Stem Cell Identity
Li Ding,Maciej Paszkowski-Rogacz,Anja Nitzsche,Mikolaj Slabicki,Anne Kristin Heninger,Ingrid de Vries,Ralf Kittler,Magno Junqueira,Andrej Shevchenko,Herbert Schulz,Norbert Hubner,Michael Xavier Doss,Agapios Sachinidis,Juergen Hescheler,Roberto Iacone,Konstantinos Anastassiadis,A. Francis Stewart,M. Teresa Pisabarro,Antonio Caldarelli,Ina Poser,Mirko Theis,Frank Buchholz +21 more
TL;DR: A genome-scale RNAi screen for a global survey of genes affecting ESC identity via alteration of Oct4 expression shows that the Paf1C binds to promoters of key pluripotency genes, where it is required to maintain a transcriptionally active chromatin structure.
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A Genome-Scale DNA Repair RNAi Screen Identifies SPG48 as a Novel Gene Associated with Hereditary Spastic Paraplegia
Mikolaj Slabicki,Mirko Theis,Dragomir B. Krastev,Sergey A. Samsonov,Emeline Mundwiller,Emeline Mundwiller,Emeline Mundwiller,Magno Junqueira,Maciej Paszkowski-Rogacz,Joan Teyra,Anne-Kristin Heninger,Ina Poser,Fabienne Prieur,Jeremy Truchetto,Jeremy Truchetto,Jeremy Truchetto,Christian Confavreux,Cecilia Marelli,Alexandra Durr,Jean Philippe Camdessanche,Alexis Brice,Andrej Shevchenko,M. Teresa Pisabarro,Giovanni Stevanin,Frank Buchholz +24 more
TL;DR: A novel gene in a genome-wide, double-strand break DNA repair RNAi screen is identified and shown to be involved in the neurological disease hereditary spastic paraplegia.
Dbf4-Dependent Cdc7 Kinase Links DNA Replication to the Segregation of Homologous Chromosomes in Meiosis I
Joao Matos,Jesse J. Lipp,Aliona Bogdanova,Sylvine Guillot,Elwy Okaz,Magno Junqueira,Andrej Shevchenko,Wolfgang Zachariae +7 more
TL;DR: It is shown that in yeast, the Dbf4-dependent Cdc7 kinase (DDK) provides a link between premeiotic S phase, recombination, and monopolar attachment and activation of DDK both initiates DNA replication and commits meiotic cells to reductional chromosome segregation in the first division of meiosis.
189
A genomic toolkit to investigate kinesin and myosin motor function in cells
Zoltan Maliga,Magno Junqueira,Yusuke Toyoda,Andreas Ettinger,Felipe Mora-Bermúdez,Robin W. Klemm,Andrej Vasilj,Elaine Guhr,Itziar Ibarlucea-Benitez,Ina Poser,Ezio Bonifacio,Wieland B. Huttner,Andrej Shevchenko,Anthony A. Hyman +13 more
TL;DR: This work generated a library of 243 amino- and carboxy-terminally tagged mouse and human bacterial artificial chromosome transgenes to establish 227 stably transfected HeLa cell lines, 15 mouse embryonic stem cell lines and 1 transgenic mouse line, providing a set of validated resources and candidate molecular pathways to investigate motor protein function across cell lineages.
117
Protein identification pipeline for the homology-driven proteomics.
Magno Junqueira,Victor Spirin,Tiago Santana Balbuena,Tiago Santana Balbuena,Henrik Thomas,Ivan Adzhubei,Shamil R. Sunyaev,Andrej Shevchenko +7 more
TL;DR: This paper addresses practical aspects of automated homology-driven protein identifications by LC-MS/MS on a hybrid LTQ Orbitrap mass spectrometer.
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