Magdi H. Yacoub
National Institutes of Health
1283 Papers
16.5K Citations
Magdi H. Yacoub is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Transplantation & Medicine. The author has an hindex of 109, co-authored 1267 publications. Previous affiliations of Magdi H. Yacoub include Royal Free Hospital & Hammersmith Hospital.
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Papers
Myocardial dysfunction in donor hearts. A possible etiology.
V. J. Owen,Paul B. J. Burton,Martin C. Michel,Oliver Zolk,Michael Böhm,John Pepper,Paul J.R. Barton,Magdi H. Yacoub,Sian E. Harding +8 more
TL;DR: Increased activity of the inhibitory G protein Gialpha is a significant contributory factor for impaired contractility in these acutely failing donor hearts.
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Left ventricular assist device-induced molecular changes in the failing myocardium.
TL;DR: Significant progress has been made toward revealing molecular changes associated with myocardial recovery from heart failure, and the unique research opportunities offered by left ventricular assist device analysis are beginning to distinguish changesassociated with recovery from those of mechanical unloading alone.
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Impact of pregnancy-related heart failure on humoral immunity: Clinical relevance of G3-subclass immunoglobulins in peripartum cardiomyopathy
Rahat S. Warraich,Karen Sliwa,Albertino Damasceno,Robert D. Carraway,Bruce Sundrom,Gulnaz Arif,Raffique Essop,Aftab A. Ansari,James D. Fett,Magdi H. Yacoub +9 more
TL;DR: In patients with peripartum cardiomyopathy, the impact of pregnancy-related HF on humoral immunity is not subclass-restricted, however, raised levels of IgG3s may be of prognostic value in clinical PPCM.
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Demonstration by western blotting of antiheart antibodies before and after cardiac transplantation.
Michael J. Dunn,Marlene L. Rose,Najma Latif,Samantha J. Bradd,Carol Lovegrove,Clive Seymour,Ariala Pomerance,Magdi H. Yacoub +7 more
TL;DR: Comparison ofWestern blotting with immunofluorescent detection of antibodies on frozen sections revealed that the Western blotting procedure is more sensitive and results are easier to interpret.
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Cytoskeletal Protein 4.1R Affects Repolarization and Regulates Calcium Handling in the Heart
Mark A. Stagg,Edward A. Carter,Nadia Sohrabi,Urszula Siedlecka,Gopal K. Soppa,Fiona Mead,Narla Mohandas,Pamela M. Taylor-Harris,Anthony J. Baines,Pauline M. Bennett,Magdi H. Yacoub,Jennifer C. Pinder,Cesare M. Terracciano +12 more
TL;DR: An unexpected and novel role for the cytoskeletal protein 4.1R in modulating the functional properties of several cardiac ion transporters with consequences on cardiac electrophysiology and with possible significant roles during normal cardiac function and disease is indicated.
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