Magdi H. Yacoub
National Institutes of Health
1283 Papers
16.5K Citations
Magdi H. Yacoub is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Transplantation & Medicine. The author has an hindex of 109, co-authored 1267 publications. Previous affiliations of Magdi H. Yacoub include Royal Free Hospital & Hammersmith Hospital.
Chat about Author
Papers
Effects of chronic administration of clenbuterol on function and metabolism of adult rat cardiac muscle
Gopal K. Soppa,Ryszard T. Smolenski,Najma Latif,Ada H.Y. Yuen,Aalya Malik,Joanna Karbowska,Zdzislaw Kochan,Cesare M. Terracciano,Magdi H. Yacoub +8 more
TL;DR: It is shown that chronic administration of Clen induces cellular hypertrophy and increases oxidative carbohydrate utilization together with an increase in sarcoplasmic reticulum Ca(2+) content, which results in increased amplitude of the Ca( 2+) transients.
73
Risk of lymphoid neoplasia after cardiothoracic transplantation. a cohort study of the relation to Epstein-Barr virus.
Anthony J. Swerdlow,Craig D. Higgins,Beverley J. Hunt,Thomas Ja,Margaret Burke,Dorothy H. Crawford,Magdi H. Yacoub +6 more
TL;DR: The risk factors found for LPD accord with EBV etiology and with greater hazard from primary infection than from reactivation, and a second non-Hodgkin's lymphoid neoplasm seems also to be a consequence of transplantation and immunosuppression but is unlikely to be due to first infection by a ubiquitous agent.
72
Transforming growth factor beta 1 and hyaluronan oligomers synergistically enhance elastin matrix regeneration by vascular smooth muscle cells.
Chandrasekhar R. Kothapalli,Patricia M. Taylor,Ryszard T. Smolenski,Magdi H. Yacoub,Anand Ramamurthi +4 more
TL;DR: Transforming growth factor beta 1 (TGF-beta1) and HA oligomers, when provided concurrently, are shown to synergistically and dramatically improve elastin matrix regeneration by adult vascular SMCs, and might be great utility to therapeutic regeneration of elast in matrix networks in situ withinElastin-compromised vessels, and within tissue-engineered vascular graft replacements.
72
A quantitative gene expression profile of matrix metalloproteinases (MMPS) and their inhibitors (TIMPS) in the myocardium of patients with deteriorating heart failure requiring left ventricular assist device support.
Leanne E. Felkin,Emma J. Birks,Robert S. George,Sissie Wong,Asghar Khaghani,Magdi H. Yacoub,Paul J.R. Barton +6 more
TL;DR: High myocardial collagenase (MMP1 and MMP8) expression without compensatory changes in collagen or TIMP expression is a feature of patients requiring LVAD support and suggests collagenase activity may be an important therapeutic target in deteriorating heart failure.
72