11 Papers
Madhuri Basak is an academic researcher from Sanjay Gandhi Post Graduate Institute of Medical Sciences. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 1, co-authored 4 publications.
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Papers
Self-assembled dipeptide based fluorescent nanoparticles as a platform for developing cellular imaging probes and targeted drug delivery chaperones
Subramaniyam Sivagnanam,Kiran Das,Madhuri Basak,Tarun Mahata,Adele Stewart,Biswanath Maity,Priyadip Das +6 more
TL;DR: In this article , Boc protected tyrosine-tryptophan dipeptide-based nanoparticles (DPNPs) with structure rigidification by Zn(ii), which shifted the peptide's intrinsic fluorescent properties from the ultraviolet to the visible range.
Malabaricone C Attenuates Nonsteroidal Anti-Inflammatory Drug-Induced Gastric Ulceration by Decreasing Oxidative/Nitrative Stress and Inflammation and Promoting Angiogenic Autohealing.
Madhuri Basak,Tarun Mahata,Sreemoyee Chakraborti,Pranesh Kumar,Bolay Bhattacharya,Sandip K. Bandyopadhyay,Madhusudan Das,Adele Stewart,Sudipta Saha,Biswanath Maity +9 more
TL;DR: Malabaricone C provided significant protection against NSAID-induced gastric ulcerations impacting multiple critical signaling cascades contributing to inflammation, cell loss, extracellular matrix degradation, and angiogenic auto-healing.
A RGS7-CaMKII complex drives myocyte-intrinsic and myocyte-extrinsic mechanisms of chemotherapy-induced cardiotoxicity
Madhuri Basak,Abhishek Sengar,Kiran Das,Tarun Mahata,Manish Kumar,Dinesh Kumar,Sayan Biswas,Subhasish Sarkar,Pranesh Chitti Bharat Kumar,Priyadip Das,Adele Stewart,Biswanath Maity +11 more
TL;DR: In this article, the authors identify RGS7, upregulated in cardiac cells following chemotherapy exposure, as a key driver of chemotherapy-dependent oxidative stress, cell loss, and fibrosis in heart.
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Supramolecular Structures Generated via Self-Assembly of a Cell Penetrating Tetrapeptide Facilitate Intracellular Delivery of a Pro-apoptotic Chemotherapeutic Drug
Subramaniyam Sivagnanam,Madhuri Basak,Abilesh Kumar,Kiran Das,Tarun Mahata,Priya Rana,Abhishek Singh Sengar,Soumyajit Ghosh,Mahesh Subramanian,Adele Stewart,Biswanath Maity,Priyadip Das +11 more
- 20 Sep 2021
TL;DR: An ultrashort cell-penetrating tetrapeptide is synthesized, with Lys as a cationic amino acid, and the self-assembly property of the BOC-protected (L1) and -deprotected (L2) analogues is studied, providing an important proof of principle, identifying L1/L2 as drug delivery matrices.
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RGS7 balances acetylation/de-acetylation of p65 to control chemotherapy-dependent cardiac inflammation
Madhuri Basak,Kiran Das,Tarun Mahata,Dinesh Kumar,Nupur Nagar,Krishna Mohan Poluri,Pranesh Chitti Bharat Kumar,Priyadip Das,Adele Stewart,Biswanath Maity +9 more
- 17 Aug 2023
TL;DR: While R GS7 overexpression in heart resulted in sterile inflammation, fibrotic remodeling, and compromised left-ventricular function, activation of SIRT1 counteracted the detrimental impact of RGS7 in heart confirming that RGS 7 increases acetylation of Sirt1 substrates and thereby drives cardiac dysfunction.
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