Mabel Brown-John
University of British Columbia
6 Papers
183 Citations
Mabel Brown-John is an academic researcher from University of British Columbia. The author has contributed to research in topics: Genome & Bacterial artificial chromosome. The author has an hindex of 6, co-authored 6 publications. Previous affiliations of Mabel Brown-John include BC Cancer Agency.
Chat about Author
Papers
A set of BAC clones spanning the human genome
Martin Krzywinski,Ian Bosdet,Duane E. Smailus,Readman Chiu,Carrie Mathewson,Natasja Wye,Sarah Barber,Mabel Brown-John,Susanna Chan,Steve Chand,Alison Cloutier,Noreen Girn,Darlene Lee,Amara Masson,Michael Mayo,Teika Olson,Pawan Pandoh,Anna Liisa Prabhu,Eric F.P.M. Schoenmakers,Miranda Tsai,Donna G. Albertson,Wan L. Lam,Chik On Choy,Kazutoyo Osoegawa,Shaying Zhao,Pieter J. de Jong,Jacqueline E. Schein,Steven J.M. Jones,Marco A. Marra +28 more
TL;DR: This work has generated a fingerprint-validated set of 32 855 BAC clones spanning the human genome, anticipating that it will generally facilitate FISH or array-CGH-based identification and characterization of chromosomal alterations relevant to disease.
Integrated and sequence-ordered BAC- and YAC-based physical maps for the rat genome
Martin Krzywinski,John W. Wallis,Claudia Gosele,Claudia Gosele,Ian Bosdet,Readman Chiu,Tina Graves,Oliver Hummel,Dan Layman,Carrie Mathewson,Natasja Wye,Baoli Zhu,Derek Albracht,Jennifer Asano,Sarah Barber,Mabel Brown-John,Susanna Chan,Steve Chand,Alison Cloutier,Jonathon Davito,Chris Fjell,Tony Gaige,Detlev Ganten,Noreen Girn,Kurtis Guggenheimer,Heinz Himmelbauer,Thomas Kreitler,Thomas Kreitler,Stephen Leach,Darlene Lee,Hans Lehrach,Michael Mayo,Kelly Mead,Teika Olson,Pawan Pandoh,Anna Liisa Prabhu,Heesun Shin,Simone Tänzer,Jason Thompson,Miranda Tsai,Jason Walker,George S. Yang,Mandeep Sekhon,LaDeana W. Hillier,Heike Zimdahl,Heike Zimdahl,Andre Marziali,Kazutoyo Osoegawa,Shaying Zhao,Asim Sarosh Siddiqui,Pieter J. de Jong,Wes Warren,Elaine R. Mardis,John Douglas Mcpherson,Richard K. Wilson,Norbert Hubner,Steven J.M. Jones,Marco A. Marra,Jacqueline E. Schein +58 more
TL;DR: The fingerprint map is a high-resolution integrative data resource that provides genome-ordered associations among BAC, YAC, and PAC clones and the assembled sequence of the rat genome.
A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells.
Asim Siddiqui,Jaswinder Khattra,Allen Delaney,Yongjun Zhao,Caroline R. Astell,Jennifer Asano,Ryan Babakaiff,Sarah Barber,Jaclyn Beland,Slavita Bohacec,Mabel Brown-John,Steve Chand,David L. Charest,Anita M. Charters,Rebecca Cullum,Noreen Dhalla,Ruth Featherstone,Daniela S. Gerhard,Brad G. Hoffman,Robert A. Holt,Juan Hou,Byron Yu-Lin Kuo,Lisa L.C. Lee,Stephanie Lee,Derek Leung,Kevin Ma,Corey Matsuo,Michael Mayo,Helen McDonald,Anna Iiisa Prabhu,Pawan Pandoh,Gregory J. Riggins,Teresa Ruiz de Algara,James L Rupert,Duane E. Smailus,Jeffrey L Stott,Miranda Tsai,Richard Varhol,Pavle Vrljicak,David H. W. Wong,Mona K. Wu,Yuanyun Xie,George S. Yang,Ida Zhang,Martin Hirst,Steven J.M. Jones,Cheryl D. Helgason,Elizabeth M. Simpson,Pamela A. Hoodless,Marco A. Marra +49 more
TL;DR: The visual cortex, pancreas, mammary gland, preimplantation embryo, and placenta contain the largest number of differentially expressed transcripts, 25% of which are previously undescribed loci.
Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling
Ryan D. Morin,Elbert Chang,Anca Petrescu,Nancy Y. Liao,Malachi Griffith,Robert Kirkpatrick,Yaron S.N. Butterfield,Alice C. Young,Jeffrey L Stott,Sarah Barber,Ryan Babakaiff,Mark Dickson,Corey Matsuo,David H. W. Wong,George S. Yang,Duane E. Smailus,Keith Wetherby,Peggy N. Kwong,Jane Grimwood,Charles P. Brinkley,Mabel Brown-John,Natalie D. Reddix-Dugue,Michael Mayo,Jeremy Schmutz,Jaclyn Beland,Morgan Park,Susan Gibson,Teika Olson,Gerard G. Bouffard,Miranda Tsai,Ruth Featherstone,Steve Chand,Asim Sarosh Siddiqui,Wonhee Jang,Edward B. Lee,Steven L. Klein,Robert W. Blakesley,Barry R. Zeeberg,Sudarshan Narasimhan,John N. Weinstein,Christa Pennacchio,Richard M. Myers,Eric D. Green,Lukas Wagner,Daniela S. Gerhard,Marco A. Marra,Steven J.M. Jones,Robert A. Holt +47 more
TL;DR: It is found that the paralogs that have been lost since the tetraploidization event are enriched for several molecular functions, but have found no such enrichment in the extantParalogs.
Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data
Agnes Baross,Allen Delaney,H. Irene Li,Tarun Nayar,Stephane Flibotte,Hong Qian,Susanna Y. Chan,Jennifer Asano,Adrian Ally,Manqiu Cao,Patricia Birch,Mabel Brown-John,Nicole D. Fernandes,Anne Go,Giulia C. Kennedy,Sylvie Langlois,Patrice Eydoux,Jan M. Friedman,Marco A. Marra,Marco A. Marra +19 more
TL;DR: The frequency of false positive deletions was substantial, but could be greatly reduced by using the SNP genotype information to confirm loss of heterozygosity, as well as true and false positive rates of genomic copy number variant (CNV) detection.