M Voyle
Smith, Kline & French
2 Papers
19 Citations
M Voyle is an academic researcher from Smith, Kline & French. The author has contributed to research in topics: Binding site & Ligand (biochemistry). The author has an hindex of 2, co-authored 2 publications.
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Papers
A proton nuclear magnetic resonance and molecular modeling study of calmidazolium (R24571) binding to calmodulin and skeletal muscle troponin C.
TL;DR: Issues pertaining to the possible simultaneous binding of calmidazolium to both globular domains of the proteins are discussed in terms of the experimental results and the overall structures of each protein.
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A proton and fluorine-19 nuclear magnetic resonance and fluorescence study of the binding of some natural and synthetic thyromimetics to prealbumin (transthyretin).
TL;DR: Interactions between prealbumin and several thyromimetic compounds have been examined by proton magnetic resonance spectroscopy and it is suggested that the first interaction confers rigidity on the second site and reduces its ability to flex open and accommodate a second thyromic, which results in the marked negative co-operation associated with the occupancy of this site.