M. Sergio
STMicroelectronics
11 Papers
14 Citations
M. Sergio is an academic researcher from STMicroelectronics. The author has contributed to research in topics: Circulating tumor cell & Biology. The author has an hindex of 6, co-authored 9 publications.
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Papers
Molecular profiling of single circulating tumor cells with diagnostic intention
Bernhard Polzer,Gianni Medoro,Sophie Pasch,Francesca Fontana,Laura Zorzino,Aurelia Pestka,Ulrich Andergassen,Franziska Meier-Stiegen,Zbigniew T. Czyż,Zbigniew T. Czyż,Barbara Alberter,Steffi Treitschke,Thomas Schamberger,M. Sergio,Giulia Bregola,Anna Doffini,Stefano Gianni,Alex Calanca,Giulio Signorini,Chiara Bolognesi,Arndt Hartmann,Peter A. Fasching,Maria T. Sandri,Brigitte Rack,Tanja Fehm,Giuseppe Giorgini,Nicolò Manaresi,Christoph Klein,Christoph Klein +28 more
TL;DR: Microheterogeneity analysis among individual CTCs uncovered pre‐existing cells resistant to ERBB2‐targeted therapies suggesting ongoing microevolution at late‐stage disease whose exploration may provide essential information for personalized treatment decisions and shed light into mechanisms of acquired drug resistance.
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Isolation and genetic analysis of pure cells from forensic biological mixtures: The precision of a digital approach
Francesca Fontana,Cesare Rapone,Giulia Bregola,R. Aversa,A. de Meo,Giulio Signorini,M. Sergio,A. Ferrarini,Rossana Lanzellotto,Gianni Medoro,G. Giorgini,Nicolò Manaresi,Andrea Berti +12 more
TL;DR: This study reports here the development of an application-specific DEPArray™ workflow enabling the detection and recovery of pure homogeneous cell pools from simulated blood/saliva and semen/Saliva mixtures, providing full genetic match with genetic profiles of corresponding donors.
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Patent
Method of reading a capacitive sensor and related integrated circuit
M. Sergio,Nicolò Manaresi,Marco Tartagni,Roberto Canegallo +3 more
- 26 Nov 2001
TL;DR: In this article, the authors propose a method for reading a capacitive sensor and may be implemented by a circuit for biasing and reading capacitances that includes circuits for selecting a column line and a row line, and a charge amplifier producing an output voltage representing the capacitance of the selected capacitor intercepted by the selected column and row lines.
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Use of the DEPArray platform to detect, isolate, and molecularly characterize pure tumor cells from peripheral blood samples enriched using the CellSearch system.
Gianni Medoro,Steven Gross,Nicolò Manaresi,M. Sergio,Francesca Fontana,Stefano Gianni,Alex Calanca,E. Peruzzi,M. Banzi,Giulio Signorini,Chandra Rao,Jaymala Patel,J. Karkera,G. Giorgini,M. Mata,Mark Connelly +15 more
TL;DR: DEPArray achieved 100% purity, eliminating all white blood cells (WBC), in the isolation of a mixed population of tumor cell lines downstream of CellSearch enrichment, enabling molecular profiling of pure tumor cells from whole blood spiked tumor cell Lines.
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