M. Russo
10 Papers
90 Citations
M. Russo is an academic researcher. The author has contributed to research in topics: Magnetic resonance imaging & In vivo. The author has an hindex of 8, co-authored 10 publications.
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Papers
Efficacy of PHA-848125, a cyclin-dependent kinase inhibitor, on the K-Ras(G12D)LA2 lung adenocarcinoma transgenic mouse model: evaluation by multimodality imaging.
Anna Degrassi,M. Russo,Cristina Nanni,Veronica Patton,Rachele Alzani,A. M. Giusti,Stefano Fanti,Marina Ciomei,Enrico Pesenti,Gemma Texido +9 more
TL;DR: Multiodality imaging was successfully used for the preclinical assessment of PHA-848125 therapeutic efficacy on a lung adenocarcinoma mouse model and could represent a valid therapeutic approach for NSCLC patients with mutant K-ras.
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Abstract A243: Characterization of NMS‐E628, a small molecule inhibitor of anaplastic lymphoma kinase with antitumor efficacy in ALK‐dependent lymphoma and non‐small cell lung cancer models
Elena Ardini,Maria Menichincheri,Cristina De Ponti,Nadia Amboldi,Maria Beatrice Saccardo,Gemma Texido,M. Russo,Paolo Orsini,Tiziano Bandiera,Andrea Lombardi Borgia,Antonella Isacchi,Enrico Pesenti,Francesco Colotta,Paola Magnaghi,Arturo Galvani,Nerviano Medical +15 more
TL;DR: The preclinical characterization of NMS‐E628, an orally available small‐molecule inhibitor of ALK kinase activity, has favorable pharmacokinetic and toxicological properties and biodistribution analysis revealed that it is able to cross the blood‐brain barrier in different animal species.
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NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases
Gianpaolo Fogliatto,Laura Gianellini,Maria Gabriella Brasca,Elena Casale,Dario Ballinari,Marina Ciomei,Anna Degrassi,Anna De Ponti,Massimiliano Germani,Marco Guanci,Mauro Paolucci,Paolo Polucci,M. Russo,Francesco Sola,Barbara Valsasina,Carlo Visco,Fabio Zuccotto,Daniele Donati,Eduard R. Felder,Enrico Pesenti,Arturo Galvani,Sergio Mantegani,Antonella Isacchi +22 more
TL;DR: The efficacy profile of NMS-E973 suggests a potential for development in different clinical settings, including tumors that have become resistant to molecular targeted agents, particularly in cases of tumors which reside beyond the BBB.
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In Vivo Imaging of Lymph Node Migration of MNP- and 111 In-Labeled Dendritic Cells in a Transgenic Mouse Model of Breast Cancer (MMTV- Ras )
Cristina Martelli,Manuela Borelli,Luisa Ottobrini,Veronica Rainone,Anna Degrassi,M. Russo,Umberto Gianelli,Silvano Bosari,Carlo Fiorini,Daria Trabattoni,Mario Clerici,Giovanni Lucignani +11 more
TL;DR: MRI and SPECT imaging, by allowing in vivo dynamic monitoring of DC migration, could further the development and optimization of efficient anti-cancer vaccines.
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Validation of an engineered cell model for in vitro and in vivo HIF-1α evaluation by different imaging modalities.
A. Lo Dico,Silvia Valtorta,Silvia Valtorta,Cristina Martelli,Sara Belloli,Sara Belloli,Umberto Gianelli,Delfina Tosi,Silvano Bosari,Anna Degrassi,M. Russo,Isabella Raccagni,Isabella Raccagni,Giovanni Lucignani,Rosa Maria Moresco,Rosa Maria Moresco,Luisa Ottobrini,Luisa Ottobrini +17 more
TL;DR: The findings of this study indicate that the U251-HRE orthotopic murine model can be used to reliably evaluate processes modulating HIF-1α activity, using both molecular and preclinical non-invasive imaging techniques.