M. Pernot
6 Papers
M. Pernot is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 6 publications.
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Papers
Increased Capillary Permeability in Heart Induces Diastolic Dysfunction Independently of Inflammation, Fibrosis, or Cardiomyocyte Dysfunction
Alice Abelanet,Marion Camoin,Sébastien Rubin,P. Bougaran,V. Delobel,M. Pernot,Isabelle Forfar,Céline Guilbeau-Frugier,Céline Galés,Marie-Lise Bats,Marie-Ange Renault,Pascale Dufourcq,Thierry Couffinhal,Cécile Duplàa +13 more
TL;DR: An increase of endothelial permeability is responsible for mediating diastolic dysfunction pathophysiology and for aggravating detrimental effects of a high-fat diet on cardiac inflammation and metabolism.
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Decrease of Pdzrn3 is required for heart maturation and protects against heart failure
M. Pernot,Béatrice Jaspard-Vinassa,Alice Abelanet,Sébastien Rubin,Isabelle Forfar,Sylvie Jeanningros,Laura Cetran,Murielle Han-Yee Yu,Elise Balse,Stéphane N. Hatem,Pascale Dufourcq,Thierry Couffinhal,Cécile Duplàa +12 more
TL;DR: In this article , the authors showed that PDZRN3 mediates a branch of the planar cell polarity (PCP) signaling involved in tissue patterning, instructing cell polar organization within a tissue.
PHACTR-1 (Phosphatase and Actin Regulator 1) Deficiency in Either Endothelial or Smooth Muscle Cells Does Not Predispose Mice to Nonatherosclerotic Arteriopathies in 3 Transgenic Mice
Sébastien Rubin,P. Bougaran,S Martin,Alice Abelanet,V. Delobel,M. Pernot,Sylvie Jeanningros,Marie-Lise Bats,Christian Combe,Pascale Dufourcq,Stéphanie Debette,Thierry Couffinhal,Cécile Duplàa +12 more
TL;DR: Loss of PHACTR-1 function in the cells involved in vascular physiology does not appear to induce a pathological vascular phenotype, and the in vivo effect of the intronic variation described in genome-wide association studies is unlikely to involve downregulation in PHAC TR-1 expression.
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Multidisciplinary shock team approach improves long-term outcomes of patients suffering from cardiogenic shock treated by short term mechanical circulatory support (STMCS)
F. Hérion,Antoine Beurton,C. Oddos,Karine Nubret,C. Aguerreche,M. Faure,Edouard Gerbaud,M. Pernot,Julien Imbault,Amidou Domegué Ouattara +9 more
Systemic hemodynamic and cardiac biomechanics changes induced by peripheral ECLS in a total closed chest cardiogenic shock sheep model
Antoine Beurton,Marc A. Michot,F. Hérion,M. Pernot,Mario Rienzo,Thierry Couffinhal,Julien Imbault,Amidou Domegué Ouattara +7 more
TL;DR: Veno-arterial extra-Corporeal life support (VA-ECLS) is proposed as an efficient device to treat refractory cardiogenic shock (CS) as discussed by the authors .