M. Natasha Rajah
McGill University
62 Papers
37 Citations
M. Natasha Rajah is an academic researcher from McGill University. The author has contributed to research in topics: Episodic memory & Medicine. The author has an hindex of 15, co-authored 44 publications. Previous affiliations of M. Natasha Rajah include Douglas Mental Health University Institute & Helen Wills Neuroscience Institute.
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Papers
Maintenance, reserve and compensation: the cognitive neuroscience of healthy ageing
Roberto Cabeza,Marilyn S. Albert,Sylvie Belleville,Fergus I. M. Craik,Audrey Duarte,Cheryl L. Grady,Ulman Lindenberger,Lars Nyberg,Denise C. Park,Patricia A. Reuter-Lorenz,Michael D. Rugg,Jason Steffener,M. Natasha Rajah +12 more
TL;DR: Age-related changes in cognitive ability are the focus of a growing field of research and the aim is to promote clarity in the field by agreeing upon consensual definitions for three widely discussed concepts: maintenance, compensation and reserve.
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Region-specific changes in prefrontal function with age: a review of PET and fMRI studies on working and episodic memory
M. Natasha Rajah,Mark D'Esposito +1 more
TL;DR: A qualitative meta-analytic review of all the functional magnetic resonance imaging ageing studies and positron emission tomography ageing studies of WM and episodic memory that report PFC activation indicated that in normal ageing distinct PFC regions exhibit different patterns of functional change, suggesting that age-related changes in PFC function are not homogeneous in nature.
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Association between prefrontal activity and volume change in prefrontal and medial temporal lobes in aging and dementia: A review
David Maillet,M. Natasha Rajah +1 more
TL;DR: It is concluded that PFC activity is related to age-related changes in local and distal GM volume reductions and that consideration of these structural measures aids the interpretation of fMRI results.
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Sex and gender differences in cognitive and brain reserve: Implications for Alzheimer's disease in women.
TL;DR: It is discussed how traditional reserve contributors are gendered and may not capture factors that support cognition in aging women and evidence that greater reserve may be more beneficial in lowering AD risk in women, although more research is needed.
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Age-related changes in prefrontal cortex activity are associated with behavioural deficits in both temporal and spatial context memory retrieval in older adults
TL;DR: The fMRI results suggest that age-related deficits in both spatial and temporal context retrieval may be linked to functional changes in right dorsolateral and left medial anterior PFC (APFC) function, and imply that older adults attempt to compensate for these deficits by engaging left dorsol lateral PFC during spatial context retrieval and right APFC during temporal context retrieved.
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