M. Lis
Université de Montréal
54 Papers
918 Citations
M. Lis is an academic researcher from Université de Montréal. The author has contributed to research in topics: Beta-Lipotropin & Medicine. The author has an hindex of 20, co-authored 44 publications.
Chat about Author
Papers
Biosynthesis of beta-endorphin from beta-lipotropin and a larger molecular weight precursor in rat pars intermedia.
P Crine,Christina Gianoulakis,Nabil G. Seidah,F. Gossard,P.D. Pezalla,M. Lis,Michel Chrétien +6 more
TL;DR: From the kinetics of the maturation of the initial precursor, it is concluded that the initial cleavage of the 30,000-dalton peptide gives rise to beta-lipotropin and the 18,000 -dalton form of corticotropin.
159
From β-lipotropin to β-endorphin and 'pro-opio-melanocortin'
M. Chrétien,Suzanne Benjannet,F. Gossard,Christina Gianoulakis,Philippe Crine,M. Lis,Nabil G. Seidah +6 more
TL;DR: It is shown unambiguously that β-endorphin is the result of a maturation process from the large precursor, while β-LPH is an important and transient intermediary in the study of peptide hormone biosynthesis.
145
Effects of thyrotropin-releasing hormone on behavioral and hormonal changes induced by β-endorphin
Y. Taché,M. Lis,Robert Collu +2 more
TL;DR: Results do not seem to be related to an interaction of TRH with opiate receptors since the tripeptide added in vitro to rat brain homogenates did not alter the specific binding of 3 H-naloxone nor affect the displacement by β-endorphin of such binding.
91
Concomitant synthesis of beta-endorphin and alpha-melanotropin from two forms of pro-opiomelanocortin in the rat pars intermedia.
TL;DR: In the pars intermedia of rat pituitary glands, two forms of a common precursor for corticotropin (ACTH) and beta-lipotropin with apparent molecular weights of 34,000 and 36,000 were resolved by sodium dodecyl sulfate/acrylamide gradient slab gel electrophoresis and found to represent two glycoprotein variants of similar polypeptides differing in the number of asparagine-linked carbohydrate moieties.
90
Free and conjugated plasma and urinary dopamine in human hypertension.
TL;DR: The elevated urinary free and total DA excretions in PA patients returned toward normal when their adrenal adenomas were removed, and the elevated plas...
83