M. Larbig
Fraunhofer Society
5 Papers
82 Citations
M. Larbig is an academic researcher from Fraunhofer Society. The author has contributed to research in topics: Environmental exposure & Medicine. The author has an hindex of 5, co-authored 5 publications.
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Papers
Validation of an environmental exposure unit for controlled human inhalation studies with grass pollen in patients with seasonal allergic rhinitis.
Norbert Krug,H. Loedding,Jens M. Hohlfeld,M. Larbig,A. Buckendahl,Philipp Badorrek,H. Geldmacher,W. Behnke,Wilhelm Dunkhorst,Horst Windt,Birgit Luettig,Wolfgang Koch +11 more
TL;DR: There is an increasing need for allergen inhalation systems to perform basic clinical research and test anti‐allergic drugs under well‐controlled conditions, which requires stability of environmental conditions like temperature and humidity, as well as allergenic concentration and reproducible induction of allergic symptoms.
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Diagnostic value of outcome measures following allergen exposure in an environmental challenge chamber compared with natural conditions.
Jens M. Hohlfeld,T. Holland-Letz,M. Larbig,M. Lavae-Mokhtari,Eddy A. Wierenga,Martien L. Kapsenberg,R. van Ree,Norbert Krug,Albrecht Bufe +8 more
TL;DR: Hohlfeld et al. as discussed by the authors investigated and compared the diagnostic value (specificity, sensitivity, and reproducibility) of clinical endpoints and biomarkers both following allergen provocation in an environmental challenge chamber (ECC) and under natural conditions.
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The Toll-Like Receptor-2/6 Agonist Macrophage-Activating Lipopeptide-2 Cooperates with IFN-γ to Reverse the Th2 Skew in an In Vitro Allergy Model
TL;DR: Data indicate that a former allergen-dependent Th2 reaction can be reversed toward a Th1-type response by an appropriate treatment of DC, and is potentially useful for treating diseases associated with misled immunologic responses.
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Effect of loteprednol etabonate nasal spray suspension on seasonal allergic rhinitis assessed by allergen challenge in an environmental exposure unit.
Norbert Krug,Jens M. Hohlfeld,H. Geldmacher,M. Larbig,R. Heermann,N. LaVallee,D. T. Nguyen,U. Petzold,Robert Hermann +8 more
TL;DR: This study assesses the clinical efficacy and safety of three different doses of LE nasal spray in seasonal allergic rhinitis (SAR).
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Facial thermography is a sensitive tool to determine antihistaminic activity: comparison of levocetirizine and fexofenadine
M. Larbig,Bernard Burtin,Laurent Martin,Holger Stamm,Birgit Luettig,Jens M. Hohlfeld,Norbert Krug +6 more
TL;DR: Facial thermography is an objective, non-invasive and sensitive method to study antihistaminic activity at the nose level and Levocetirizine and fexofenadine demonstrate the same activity at 2 h after drug intake, but levocetirIZine has a more sustained activity at 24 h.
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