M. Hofmann
10 Papers
60 Citations
M. Hofmann is an academic researcher. The author has contributed to research in topics: Chemistry & Analytical Chemistry (journal). The author has an hindex of 5, co-authored 7 publications.
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Papers
Superparamagnetic nanoparticles for biomedical applications: Possibilities and limitations of a new drug delivery system
TL;DR: The characteristics and applications of SPION in the biomedical sector are introduced and discussed, and superparamagnetic nanoparticles based on a core consisting of iron oxides that can be targeted through external magnets are discussed.
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Critical raw materials: A perspective from the materials science community
TL;DR: In this paper, the authors introduce the topic of materials criticality for the special issue of sustainable materials and technologies and observe how the criticality of raw materials is perceived and handled within Materials Science.
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Intraarticular application of superparamagnetic nanoparticles and their uptake by synovial membrane—an experimental study in sheep
Katja Schulze,Annette Koch,Bernhard Schöpf,A. Petri,Benedikt Steitz,Mathieu Chastellain,M. Hofmann,Heinrich Hofmann,Brigitte von Rechenberg +8 more
TL;DR: A superparamagnetic iron oxide nanoparticle, coated with polyvinyl alcohol, and its fluorescently functionalized analogue (amino-PVA-Cy3.5-SPION) were compared in vivo as proof of principle for future use in magnetic drug targeting in inflammatory joint diseases.
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Uptake and biocompatibility of functionalized poly(vinylalcohol) coated superparamagnetic maghemite nanoparticles by synoviocytes in vitro.
Katja Schulze,Annette Koch,Alke Petri-Fink,Benedikt Steitz,Sarah W. Kamau,Michael O. Hottiger,Monika Hilbe,Lloyd Vaughan,M. Hofmann,Heinrich Hofmann,Brigitte von Rechenberg +10 more
TL;DR: Results indicate that functionalized amino PVA-coated SPION are biocompatible, were successfully internalized by synoviocytes and hold promise for future biomedical applications utilizing magnetic drug targeting in joint disease.
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Systemic distribution and elimination of plain and with Cy3.5 functionalized poly(vinyl alcohol) coated superparamagnetic maghemite nanoparticles after intraarticular injection in sheep in vivo.
Daniel Hellstern,Katja Schulze,Bernhard Schöpf,Alke Petri-Fink,Benedikt Steitz,Sarah W. Kamau,Monika Hilbe,Sabine Koch-Schneidemann,Lloyd Vaughan,Michael O. Hottiger,M. Hofmann,Heinrich Hofmann,Brigitte von Rechenberg +12 more
TL;DR: The results indicated that the iron component of the SPION is possible to be incorporated into the physiologic iron metabolism after reabsorption in the proximal tubule system of the kidney and that concentration levels of Cy3.5 are too low to be detected throughout the body.
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