M. Gore
Wistar Institute
5 Papers
137 Citations
M. Gore is an academic researcher from Wistar Institute. The author has contributed to research in topics: Epitope & Virus. The author has an hindex of 4, co-authored 4 publications.
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Papers
Induction of rabies virus-specific T-helper cells by synthetic peptides that carry dominant T-helper cell epitopes of the viral ribonucleoprotein.
Hildegund C.J. Ertl,Bernhard Dietzschold,M. Gore,Laszlo Otvos,Jovi K. Larson,William H. Wunner,Hilary Koprowski +6 more
TL;DR: Inoculation of mice with peptides bearing immunodominant T-helper cell epitopes resulted in an accelerated and enhanced neutralizing antibody response upon booster immunization with inactivated rabies virus.
141
Structural and immunological characterization of a linear virus-neutralizing epitope of the rabies virus glycoprotein and its possible use in a synthetic vaccine.
Bernhard Dietzschold,M. Gore,D. Marchadier,H.-S. Niu,H. M. Bunschoten,Laszlo Otvos,William H. Wunner,H. J. C. Ertl,A. D. M. E. Osterhaus,Hilary Koprowski +9 more
TL;DR: A linear epitope recognized by the virus-neutralizing monoclonal antibody 6-15C4 within the primary sequence of the G protein from the Evelyn-Rokitnicki-Abelseth strain of rabies virus induced protective immunity against lethal rabiesirus challenge infection in mice.
136
Biological characterization of human monoclonal antibodies to rabies virus.
Bernhard Dietzschold,M. Gore,P Casali,Y Ueki,Charles E. Rupprecht,A L Notkins,Hilary Koprowski +6 more
TL;DR: Rabies virus antigen-specific human monoclonal antibodies that recognized either viral glycoprotein, ribonucleoprotein, or matrix proteins were generated and neutralized a variety of rabies viruses and protected laboratory rodents against lethal rabies virus infection.
117
•Journal Article
Breakage in alpha-helix: a recognition site for anti-rabies virus ribonucleoprotein antibody.
TL;DR: It was found that only synthetic peptides with disrupted helical structure in the antigenic region were active on immunoblot assay, performed against a natural anti-protein monoclonal antibody (MAb) and provoked virus-neutralizing antibody production.
5
The Epstein-Barr Virus Glycoprotein BDLF2 Is Essential for Efficient Viral Spread in Stratified Epithelium
Joshua J. Walston,I. Hayman,M. Gore,Mary Ferguson,Rachel M. Temple,Jason Liao,Samina Alam,Craig Meyers,Sharof M. Tugizov,Lindsey M. Hutt-Fletcher,Clare E. Sample +10 more
TL;DR: In this paper , a recombinant version of the Epstein-Barr virus (EBV) was found to have little effect on the EBV life cycle but severely restricted the number of infected cells in organotypic cultures.