M. E. Van Der Tol
Utrecht University
9 Papers
144 Citations
M. E. Van Der Tol is an academic researcher from Utrecht University. The author has contributed to research in topics: Granulocyte & Antibody. The author has an hindex of 6, co-authored 9 publications.
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Papers
•Journal Article
A Synthetic Lipopolysaccharide-Binding Peptide Based on Amino Acids 27–39 of Serum Amyloid P Component Inhibits Lipopolysaccharide-Induced Responses in Human Blood
TL;DR: Pep27-39, a 13-mer peptide consisting of amino acids 27-39 of SAP, competitively inhibited the binding of LPS to SAP and significantly inhibited ReLPS-induced responses in phagocytes in the presence of serum, as well as in human whole blood.
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Forty-five years of Duchenne muscular dystrophy in The Netherlands
J.C. van den Bergen,H.B. Ginjaar,A. J. van Essen,R.F. Pangalila,I.J.M. de Groot,Peter J. Wijkstra,Marianne Zijnen,Nicole A. M. Cobben,Mike J. Kampelmacher,B.H.A. Wokke,I.F.M. de Coo,Johanna M. Fock,A. M. C. Horemans,M. E. Van Der Tol,Elizabeth Vroom,M.E.B. Rijlaarsdam,Chiara S. M. Straathof,Erik H. Niks,Jan J.G.M. Verschuuren +18 more
TL;DR: Detailed information about the disease course of DMD patients is given, evidence for the positive effect of steroid treatment and mechanical ventilation is provided and the use of patient registries as a valuable resource for evaluating improvements in care is supported.
The role of tumour necrosis factor in the kinetics of lipopolysaccharide-mediated neutrophil priming in whole blood.
TL;DR: To study the balance between neutrophil activation and LPS neutralization a sensitive chemiluminescence assay was used in a whole blood system and found LPS was able to prime neutrophils for enhanced oxidative burst in whole blood with an optimum incubation time of 25 min but was neutralized very rapidly.
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•Journal Article
Tumour necrosis factor triggers granulocytes to internalize complement-coated virus particles.
TL;DR: It is proposed that TNF-alpha and GM-CSF act as effective modulators of PMH to enhance virus removal, especially in inflammatory sites.
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•Journal Article
Modulation of lipopolysaccharide binding to human granulocytes.
TL;DR: Evidence is provided that LPS binding and activation of PMN involves protein structures at the cell surface different from CD14, and that granules constitute a pool of LPS-binding proteins that can be translocated to the cellsurface upon stimulation.
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